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Herbal Remedies Natural Health Newsletter, June 2008, Issue 281

Herbal Remedies June 2008 Natural Health Newsletter Issue 281 Sponsored by www.HerbalRemedies.com Toll Free for orders 1-866-467-6444 Issue Editor - Heather Bowman

Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books Vitamin K Found to Help Skin Health - Click here for full story. Vitamin D Shown to Help Mental Health - Click here for full story. Pycnogenol® Found to Help Joint Health - Click here for full story. Fish Oil During Pregnancy Improves Infant Eye and Brain Health - Click here for full story. CoQ10 May Offer Help for Fatigue During Exercise - Click here for full story. Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies Be sure to check out our Overstocked clearance items! OVERSTOCKED Give your skin a natural glow with Burt's Bees Products. We are your #1 Headquarters for your complete line of Burt’s Bees Products for that all around natural glow!! • Herbal Remedies has four new vendors be sure to check them out: Herbal Remedies USA Products , Dr Bronner’s Castile Soaps , Tints of Nature/ Naked Earth Permanent Organic Hair Color Products, and Burt's Bees Men's Products Products Spotlight – Want to save time in a bottle? The first step to youthfull skin is by using Tanning Lotion, Tanning Oil, Sun Tan Lotion, Sunscreen or Suntan Lotion to keep your skin young and fresh looking. "The American Academy of Dermatology suggests that, regardless of skin type, a broad-spectrum (protects against UVA and UVB rays) sunscreen with a Sun Protection Factor (SPF) of at least 15 should be used year-round." (Source: American Academy of Dermatology). Protect your skin from the sun with ingredients made from under the sun! Current Event News: Don’t let this allergy season keep you indoors! An allergy is a response by the body’s immune system to a substance that is not usually considered harmful. When a person has an allergic response, the immune system identifies the substance (allergen) as an invader and the white blood cells begin to attack it. Since the white blood cells cause more damage to the body instead of helping it, the allergic response becomes a disease in itself. Almost any substance can act as an allergen. Allergies can affect one’s quality of life and can adversely affect productivity on the job or at school. Don’t let your allergies prison you and protect yourself naturally without the drowsy feeling of prescriptions! Blistering Hot Summer Savings with our Coupon Savings and with these kind of prices you can afford to stock up! QUESTIONS AND ANSWERS Q: Subject: Hello Hi Does Nisim hair care products actually regrow hair or does it only stop hair loss and thicken hair? Many thanks A: Dear Customer, Nisim shampoo and stimulating extract were clinically proven to regrow hair on 85.7% of those tested. Nisim Shampoo by itself will control excessive hair loss in one week guaranteed. The active ingredients in Nisim's products are natural organic herbal extracts. The entire line of Nisim hair care products are safe for permed, colored or chemically treated hair. All my best, Thank you for your interest in Herbal Remedies.com and the opportunity to serve you. Heather * The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products. Our Sponsors Enter coupon code "NL061808" when checking out to obtain discounts on your next purchase from http://www.HerbalRemedies.com. How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.99 automatic shipping discount for orders over $95. The more you order the more you save!!! All previous sales and previous sale items excluded , only one coupon code per order

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Vitamin K Found to Help Skin Health By Greg Arnold, DC, CSCS, May 13, 2008, abstracted from “Matrix GLA protein is involved in elastic fiber calcification in the dermis of pseudoxanthoma elasticum patients” in the October 2007 issue of Laboratory Investigation Pseudoxanthoma elasticum (PXE) is an inherited disorder that causes severe wrinkling of the skin and also affects the eyes, cardiovascular and digestive systems. It induces wrinkles on the skin and in the body by causing elastic tissue to become filled with calcium and other minerals (1). Plastic surgery and laser treatments are prescribed methods of dealing with the skin-wrinkling effects of PXE(2). Now a new study(3) has found that vitamin K , normally associated with joint health ( 4), blood clotting (5) and blood vessel health (6), may also help patients with PXE improve overall skin health by helping maintain function of a protein called Matrix GLA protein (MGP). MGP is dependent on vitamin K for proper function(7) and plays “a well-recognized role” in preventing mineralization of connective tissues(8). Previous research showed that a genetic defect in vitamin K recycling increases wrinkle formation through elastic fiber calcification(9). Building on these findings, researchers drew blood and acquired skin samples from 30 patients without PXE and 30 patients with PXE. The researchers found that patients with PXE had MGP levels that were 29% lower than patients without PXE. They also found that a form of MGP associated with healthy skin (called Gla-MGP) was “nearly absent” from patients with PXE. For the researchers, “[MGP] may have a role in preventing elastic fiber calcification” and help maintain overall skin health. And because of vitamin K’s “fundamental importance” in preventing tissue calcification of skin fibers similar to those in PXE, vitamin K would seem to play an important role in overall skin health and wrinkles. Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 PXE International Website www.pxe.org/english/View.asp?x=1526 2 “Frequently Asked Questions – Skin” posted on www.pxe.org/english/View.asp?x=1435 3 Gheduzzi D. Matrix Gla protein is involved in elastic fiber calcification in the dermis of pseudoxanthoma elasticum patients. 87: 998-1008; advance online publication, August 27, 2007; doi:10.1038/labinvest.3700667 4 Schurgers LJ. Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats. Blood 2007 Apr 1;109(7):2823-31 5 Neogi T. Low vitamin K status is associated with osteoarthritis in the hand and knee. Pediatrics 2006; 54(4): 1255-1261 6 Hall JG, Pauli RM, Wilson KM. Maternal and fetal sequelae of anticoagulation during pregnancy. Am J Med 1980;68:122–40. 7 Luo G, Ducy P, McKee MD, et al. Spontaneous calcification of arteries and cartilage in matrix gla protein. Nature 1997;386:78–81 8 Yagami K, Suh JY, Enomoto-Iwamoto M, et al. Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb. J Cell Biol 1999;147:1097–1108 9 Vanakker O, Martin L, Gheduzzi D, et al. Pseudoxanthoma elasticum-like phenotype with cutis laxa and multiple coagulation factor deficiency represents a separate genetic entity. J Invest Dermatol 2007;127:581–587

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Vitamin D Shown to Help Mental Health By Greg Arnold, DC, CSCS, May 7, 2008, abstracted from “Depression Is Associated With Decreased 25-Hydroxyvitamin D and Increased Parathyroid Hormone Levels in Older Adults” in the May 2008 issue of the Archives of General Psychiatry Recent research has found that 13% of adults over 55 years of age suffer from “significant depressive symptoms”(1) which play a prominent role in illness and death in these patients(2). While depression costs employers $51 billion each year in absenteeism and lost productivity (not including high medical and pharmaceutical bills)(3), elderly people with depression have roughly 50% higher health care costs than non-depressed seniors and costs our healthcare system nearly $22 billion a year(4). Researchers have started to look at the changing lifestyle habits of aging adults, including decreased sun exposure due to decreased outdoor activity, different housing or clothing habits, and decreased vitamin intake (5), all of which may result in decreased vitamin D blood levels. Vitamin D is thought to play a role in mental health and depression because low vitamin D blood levels lead to an increase in parathyroid hormone (PTH). High PTH levels have been found to be accompanied by depressive disorders, which usually abate once the PTH levels are brought down(6, 7). Now a new study(8) has added support to the role of vitamin D blood levels in mental health. In The Longitudinal Aging Study Amsterdam(9), 1282 men and women between 55 and 85 completed questionnaires on lifestyle and diet. They also provided blood samples, which were used to measure vitamin D blood levels. While nearly 39% of the men and nearly 57% of the women had “insufficient” blood levels of vitamin D (< 20 ng/mL), the researchers found that patients with minor depressive and major depressive symptoms had vitamin D blood levels 14% lower (19 ng/mL) than patients without any depressive symptoms (22 ng/mL). Regarding PTH levels, patients with minor depression had PTH levels that were 5% higher than non-depressed patients and 33% higher in patients with major depression. For the researchers, “depression and depression severity…is strongly associated with lower [vitamin D blood levels] and higher PTH levels, even after adjustment for age, sex, BMI, smoking status, health status, level of physical activity, and level of urbanization.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com. Reference: 1 Beekman AT, Copeland JR, Prince MJ. Review of community prevalence of depression in later life. Br J Psychiatry. 1999;174:307-311 2 Penninx BW, Beekman AT, Honig A, Deeg DJ, Schoevers RA, van Eijk JT, van Tilburg W. Depression and cardiac mortality: results from a community-based longitudinal study. Arch Gen Psychiatry. 2001;58(3):221-227 3 “Depression Programs Might Provide An Edge” posted on www.managedcaremag.com/archives/0405/0405.employers.html 4 “Elderly Depressive Symptoms – What You Need To Know” posted on http://ezinearticles.com/?Elderly-Depression-Symptoms---What-You-Need-To-Know&id=974254 5 Michelson D, Stratakis C, Hill L, Reynolds J, Galliven E, Chrousos G, Gold P. Bone mineral density in women with depression. N Engl J Med. 1996;335(16):1176-1181 6 Petersen P. Psychiatric disorders in primary hyperparathyroidism. J Clin Endocrinol Metab. 1968;28(10):1491-1495 7 Watson LC, Marx CE. New onset of neuropsychiatric symptoms in the elderly: possible primary hyperparathyroidism. Psychosomatics. 2002;43(5):413-417 8 Witte JG. Depression Is Associated With Decreased 25-Hydroxyvitamin D and Increased Parathyroid Hormone Levels in Older Adults. Arch Gen Psychiatry. 2008;65(5):508-512 9 eg DJ, van Tilburg T, Smit JH, de Leeuw ED. Attrition in the Longitudinal Aging Study Amsterdam: the effect of differential inclusion in side studies. J Clin Epidemiol. 2002;55(4):319-328

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Pycnogenol® Found to Help Joint Health By Greg Arnold, DC, CSCS, May 7, 2008, abstracted from “Treatment of osteoarthritis with Pycnogenol®. The SVOS (San Valentino osteo-arthrosis study). evaluation of signs, symptoms, physical performance and vascular aspects” in the April 2008 issue of Phytotherapy Research Research continues to shine more light on the diverse health benefits of Pycnogenol ®. These benefits include helping deal with lower leg swelling(1), being effective for venous ulcers(2), showing to be comparable to prescription drugs for helping venous leg circulation(3), and benefiting both mental health (4) and healthy levels of inflammation (5). The ways that Pycnogenol® can improve your health just keep coming. A new study(6) has found that Pycnogenol® may help osteoarthritis . This joint condition is the nation’s leading cause of disability, limiting everyday activities for 16 million Americans. It results in 750,000 hospitalizations and costs our healthcare system over $51 billion each year(7). In the study, 156 patients with diagnosed arthritis were given either 100 mg of Pycnogenol® or placebo per day for three months. During this period, they completed questionnaires on arthritis pain and did an exercise treadmill test (testing how far they could walk without pain). The researchers graded ankle swelling in both groups at the beginning and end of the study. The researchers found that the pain scores decreased by 56% in the Pycnogenol® 1 group, compared to only 9.6% in the placebo group. The Pycnogenol® patients had a 191% increase in distance they could walk on the treadmill without pain (65 m to 198 m), compared to only 35% in the placebo group. Finally, ankle swelling decreased by 79% in the Pycnogenol® group, compared to only 1% in the placebo group. For the researchers, “Pycnogenol® l offers an option for reduction of treatment costs and side effects by sparing anti-inflammatory drugs” when treating osteoarthritis. Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at http://www.completechiropractichealthcare.com Reference: 1 Belcaro G. Prevention of venous thrombosis and thrombophlebitis in long-haul flights with pycnogenol. Clin Appl Thromb Hemost. 2004 Oct;10(4):373-7 2 Belcaro, G., M. R. Cesarone, et al. (2005). "Venous ulcers: microcirculatory improvement and faster healing with local use of pycnogenol((r))." Angiology 56(6): 699-705 3 Cesarone MR. Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study. Clin Appl Thromb Hemost 2006; 12(2): 205-12 4 Trebaticka J. Treatment of ADHD with French maritime pine bark extract, Pycnogenol®). Eur Child Adolesc Psychiatry. 2006 May 13; [Epub ahead of print] 5 Grimm T. Inhibition of NF-êB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol) Journal of Inflammation 2006, 3:1 (27 January 2006) 6 Belcaro G. Treatment of osteoarthritis with Pycnogenol®. The SVOS (San Valentino osteo-arthrosis study). evaluation of signs, symptoms, physical performance and vascular aspects. Phyto Res 2008; 22: 518-523. Published Online: Apr 2 2008 8:56AM DOI: 10.1002/ptr.2376 7 “Targeting Arthritis: Reducing Disability for 43 Million Americans” posted on the CDC Website www.cdc.gov/nccdphp/aag/aag_arthritis.htm

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Fish Oil During Pregnancy Improves Infant Eye and Brain Health By Greg Arnold, DC, CSCS, April 22, 2008, abstracted from “Beneficial Effects of a Polyunsaturated Fatty Acid on Infant Development: Evidence from the Inuit of Arctic Quebec” in the 2008 issue of the Journal of Pediatrics Nutrients that need to be taken by women who are pregnant to help their child’s health include vitamin C to help the immune system(1), vitamin E to help protect against mercury(2), vitamin B-3 for nervous system development(3), and calcium for bone health(4). Another crucial area of infant development is the brain, which is where fish oil comes in. Although fish oil has been found to help with blood pressure in infants(5), the fish oil fat called DHA is the primary fat found in the brain(6). And because it is very difficult for the mother to produce her own DHA for the baby until four months after birth(7), supplementing fish oil during pregnancy may be crucial to brain health in the unborn child. Research has shown that taking fish oil during pregnancy can help eye-hand coordination in infants(8). Building on these findings, a new study(9) has shown that taking fish oil during pregnancy can help brain and eye development in infants. The study included 109 pregnant mothers participating in the Environmental Contaminants and Child Development Study in Quebec from 1995-2001(10). They provided umbilical cord and breast milk samples after the birth of their baby, and also provided information about diet and lifestyle. At six months of age, the infants underwent the Teller Visual Acuity Card Test(11) and the Fagan Test of Infant Intelligence (FTII)(12). At 11 months of age, they underwent the FTII and mental and psychomotor indices of the Bayley Scales of Infant Development (BSID-II). In addition to finding higher levels of DHA in the umbilical cords versus breast milk (revealing the strong dependence by the fetus on the mother for adequate DHA intake), the length of pregnancy was increased by more than four days when umbilical cord levels of DHA reached 3% of the total fatty acid levels. Unfortunately, no data on maternal intake of DHA was assessed; only measurements from the umbilical cord and breast milk were given. Regarding infant coordination, higher DHA cord levels resulted in higher visual and coordination scores (30% higher visual acuity, 9% higher FTII scores, and 5% higher mental development scores) at 6 months, but not at 11 months. These results led the researchers to conclude that “The association of higher cord DHA concentration with more optimal visual, cognitive, and motor development is consistent with the need for substantial increases in [DHA] during the third trimester spurt of [brain development] and [eye] development. Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 Hoppu, U., M. Rinne, et al. (2005). "Vitamin C in breast milk may reduce the risk of atopy in the infant." Eur J Clin Nutr 59(1): 123-8 2 Beyrouty P. Co-consumption of selenium and vitamin E altered the reproductive and developmental toxicity of methylmercury in rats Neurotoxicity and Teratology. Available online 19 January 2006 3 Ieraci A. Nicotinamide Protects against Ethanol-Induced Apoptotic Neurodegeneration in the Developing Mouse Brain. Public Library and Science – Medicine 2006; Volume 3 Issue 4 printed online ahead of print 4 Chan G. Effects of Dietary Calcium Intervention on Adolescent Mothers and Newborns: A Randomized Controlled Trial. Obst Gynecol 2006; 108(3, Part 1):565-571 5 Damsgaard CT. Fish Oil Affects Blood Pressure and the Plasma Lipid Profile in Healthy Danish Infants. J. Nutr. 2006;136 94-99 6 Helland IB, Saugstad OD, Smith L, Saarem K, Solvoll K, Ganes T, et al. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001;108:E82. 7 Makrides M, Neumann M, Simmer K, Pater J, Gibson R. Are long-chain polyunsaturated fatty acids essential nutrients in infancy? Lancet 1995;345:1463-8 8 Dunstan JA. Cognitive assessment of children at age 2K years after maternal fish oil supplementation in pregnancy: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. doi: 10.1136/adc.2006.099085 9 Jacobson JL. Beneficial Effects of a Polyunsaturated Fatty Acid on Infant Development: Evidence from the Inuit of Arctic Quebec. Jou Ped 2008; 152: 356-364.e1 10 Muckle G, Ayotte P, Dewailly E, Jacobson SW, Jacobson JL. Prenatal exposure of the Northern Quebec Inuit infants to environmental contaminants. Environ Health Perspect 2001;109:1291-9 11 Teller DY, McDonald M, Preston K, Sebris SL, Dobson V. Assessment of visual acuity in infants and children: the acuity card procedure. Dev Med Child Neurol 1986;28:779-89 12 Fagan JF, Singer LT. Infant recognition memory as a measure of intelligence. In: Lipsitt LP, Rovee-Collier CK, editors. Advances in infancy research. Norwood, NJ: Ablex; 1983. p. 31-78

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CoQ10 May Offer Help for Fatigue During Exercise By Greg Arnold, DC, CSCS, April 18, 2008, abstracted from “Antifatigue effects of coenzyme Q10 during physical fatigue” in the April 2008 issue of Nutrition CoQ10 was first identified in 1957 and was known as “ubiquinone” because it is found everywhere in the body. It is found in the highest amounts in the heart, liver, kidneys, and pancreas and in lowest amounts in the lungs(1). While helping to maintain healthy levels of inflammation (2), CoQ10 has been found to help with mental health (3), migraines (4), heart health (5), and even blood sugar health(6). Now a new study(7) has found that CoQ10 can also help with fatigue during exercise. In the study, 17 healthy patients took either 100 mg of CoQ10, 300 mg of CoQ10, or placebo per day for 8 days. The patients exercised for two hours on a stationary bike twice per day (at 8 am and 4:30 pm) at a workload which produced 80% of their maximum heart rate. The patients filled out a visual analog scale rating fatigue from 0 (no fatigue) to 100 (complete exhaustion(8) and had blood pressure and blood samples taken after each exercise session. While there was no difference in blood pressure changes between the three groups, the researchers found that those in 300 mg group of CoQ10 reported 22% less fatigue than the placebo group and 13% less fatigue than the 100 mg group. Exact numbers were not provided by the researcher but were plotted on a bar graph. For the researchers, “oral administration of coenzyme Q10 improved subjective fatigue sensation and physical performance during fatigue-inducing workload trials” and that “administration of coenzyme Q10 might prevent unfavorable conditions as a result of physical fatigue.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 “Questions and answers about Coenzyme Q10” posted on the National Cancer Institute Website http://www.cancer.gov/cancertopics/pdq/cam/coenzymeQ10/Patient/page2 2 Wang, X.L., et al., Cosupplementation with vitamin E and coenzyme Q10 reduces circulating markers of inflammation in baboons. Am J Clin Nutr, 2004. 80(3): p. 649-55 3 Ishrat T. Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats. Printed online in Behavioural Brain Research doi:10.1016/j.bbr.2006.03.009 4 Pothmann, R. Migraine Prevention in Children and Adolescents: Results of an Open Study With a Special Butterbur Root Extract. Headache 2005; 45(3): 196-203 5 Wisloff, U., S. M. Najjar, et al. (2005). "Cardiovascular risk factors emerge after artificial selection for low aerobic capacity." Science 307(5708): 418-20 6 Petersen, K. F., D. Befroy, et al. (2003). "Mitochondrial dysfunction in the elderly: possible role in insulin resistance." Science 300(5622): 1140-2 7 Mizuno K. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition 2008; 24(4): 293-299 Do you have a question for us? If so please send in your questions to newsletter@herbalremedies.com We will answer all email ASAP!

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For assistance or to purchase products by phone call toll free in the USA 1-866-467- 6444 or World Wide 1-307-577-6444 or e-mail your questions to newsletter@herbalremedies.com. We will answer e-mails in the newsletter as space allows. Our Sponsors HerbalRemedies.com Get the finest all natural health products, get the best service, and low cost worldwide delivery. Enter coupon code "NL061808" when checking out to obtain discounts on your next purchase from www.HerbalRemedies.com How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.99 automatic shipping discount for orders over $95. The more you order the more you save!!! Only one coupon per order!