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Herbal Remedies Natural Health Newsletter, July 2006, Issue 261

Herbal Remedies July 2006 Natural Health Newsletter Issue 261 Sponsored by www.HerbalRemedies.com Toll Free for orders 1-866-467-6444 Issue Editor - Heather Bowman

Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books Study Finds Folic Acid Helps Make Healthy DNA - Click here for full story. Cranberry Now Found to Help Protect Against Cavities - Click here for full story. Study Finds Vitamin C and E Deficiencies Cause Nervous System Damage - Click here for full story. Magnesium Found to Possibly Play a Protective Role Against Asthma - Click here for full story. Milk Thistle Provides Hope in Protecting Against Lung Cancer - Click here for full story. Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies In order to show customers how much we appeciate your business and celebration of our 6th year of quality service we are holding our Customer Appreciation Month Available now for downloading our Herbal Remedies Catalog . Herbal Remedies has three new vendors be sure to check them out: Improvita , Shikai, and NatraCare Products Spotlight - Don’t you love that all natural baby smell? Don’t you wish they could bottle it? Well they have come pretty close with Original Little Sprout products ! All ORIGINAL LITTLE SPROUT products are made without any harmful ingredients such as: Sodium lauryl sulfate, propylene glycol, mineral oil, DEA or PVP. And, as an added bonus to using the safest known ingredients, THE ORIGINAL LITTLE SPROUT products boast a gentle baby fragrance using natural sunflower ingredients imported from France. So, rather than using essential oils, which are typically used in most baby products and are also known to be corrosive & cause allergic reactions, ORIGINAL LITTLE SPROUT gently allows babies to smell like babies- naturally. Current Event News: Wouldn’t it be great to have a pain management that tastes like juice or better yet is juice? In addition to its wonderful flavor, studies have shown that Black Cherries and the equivalent amount of Black Cherry extract or Black Cherry concentrate has been found to prevent attacks of gout. There have been many additional anecdotal reports of cherry extract as an effective treatment for the pain and inflammation of gout. Black Cherries contain compounds that help relieve the pain of arthritis, gout, and even headaches. The secret is in the pigments that give cherries their rich red / black hue. They belong to a class of natural dyes called anthocyanins. These compounds are being called "Mother Nature's all-natural chemotherapy agents." What more could you ask of your favorite homemade dessert or iced tea? To make your online shopping even more convenient for you we have a vast selection of products priced with you in mind in our RED HOT SALE ITEMS Be sure to check out our Irwin Naturals Annual Line Drive with prices up to 50% Off! QUESTIONS AND ANSWERS Q: Subject: Hello Could you tell me the source of rose hip extract ? Is there a natural supplement for this extract ? Does a natural intake of any food compensate for this extract . Please advice Many thanks A: Dear Customer, Wild Roses are found in various places from forests to canyons, logged wastelands and thickets. There are nine species of Roses, all of which have edible fruits and flowers, though they are not necessarily tasty. The 'hips' (fruit) follows the flower, generally appearing in the fall and resembling a tiny dried apple. Rose Hips contain more vitamin C, calcium, phosphorus, and iron than oranges, and sixty times more vitamin C than lemons. Here are a few supplements containing rose hips: Rose Hips Tincture, Rose Hips Tea, or Vitamin C Liquid, with Rose Hips Thank you for your interest in Herbal Remedies.com and the opportunity to serve you. Heather * The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products. Our Sponsors Enter coupon code "NL072406" when checking out to obtain discounts on your next purchase from http://www.HerbalRemedies.com

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Study Finds Folic Acid Helps Make Healthy DNA By Greg Arnold, DC, CSCS, June 27, 2006, abstracted from “Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers” in the June 19, 2006 issue of the British Journal of Cancer Although most commonly associated with infant health by helping prevent neural tube defects in newborns,(1) folic acid has also exhibited health benefits for the elderly by helping improve memory (2) and improving immune function.(3) Folic acid levels have even been found to mirror omega-3 fatty acid levels in the body.(4) Research has also found that folic acid may play a role in helping protect against cancer , since folic acid deficiency has been associated with breast,(5) large bowel,(6) cervix,(7) esophagus,(8) and lung(9) cancer. Now a new study(10) has found that folic acid’s role in health may lie in its ability to help insure proper DNA synthesis. Building upon previous research showing that folic acid deficiency leads to incorrect DNA synthesis in rats,(11) 30 patients were given 1.2 mg of folic acid per day and compared to 30 controls. Researchers took a number of measurements in the patients’ blood, including folic acid levels, a breakdown product of homocysteine called SAM (since high homocysteine levels increase cancer risk(12), and DNA strand instability and breakage. The researchers found that folate supplementation “significantly increased” whole blood SAM while eliciting “a significant reduction” in plasma homocysteine compared with the control group. Concerning DNA damage, the folic acid group showed “a significant decrease” in DNA synthesis disruption compared with control. No effect was seen, however, between folic acid and DNA strand instability and breakage. For the researchers, “supplementation with 1.2 mg folic acid in a healthy population resulted in a significant increase in several measures of blood folate status with a concomitant decrease in [disrupted DNA synthesis].” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. Contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com.m Reference: 1 “Spina Bifida and Anencephaly Before and After Folic Acid Mandate --- United States, 1995--1996 and 1999—2000” from MMWR Weekly 2004; 53(17): 362-365 2 “The First Ever Dementia Conference Opens In Washington, DC” posted on the Alzheimer’s Association Website www.alz.org/preventionconference/pc2005/overview.asp 3 C.J. Field, I.R. Johnson and P.D. Schley, Nutrients and their role in host resistance to infection, J Leukoc Biol 71 (2002), pp. 16–32 4 Umhau JC. The relationship between folate and docosahexaenoic acid in men. Eur J Clin Nutr. 2005 Nov 9; [Epub ahead of print] 5 Zhang SM (2003) Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst 95(5): 373–380 6 Lashner BA (1993) Red cell folate is associated with the development of dysplasia and cancer in ulcerative colitis. J Cancer Res Clin Oncol 119: 549–554 7 Van Eenwyk J (1990) Folate, vitamin C and cervical intraepithelial neoplasia. Cancer Epidemiol Biomark Prev 1: 651–652 8 Jaskiewicz K (1988) Association of esophageal cytological abnormalities with vitamin and lipotrope deficiencies in populations at risk for oesophageal cancer. Anticancer Res 8: 711–716 9 Duthie SJ (1999) Folic acid deficiency and cancer: mechanisms of DNA instability. Br Med Bull 55(3): 578–592 10 Baston GP. Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers British Journal of Cancer (2006) 94, 1942-1947 11 Melnyk S (1999) Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells. Cancer Lett 146(1): 35–44 12 Zhang W. Expression profiling of homocysteine junction enzymes in the NCI60 panel of human cancer cell lines. Cancer Res. 2005 Feb 15;65(4):1554-60.

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Cranberry Now Found to Help Protect Against Cavities By Greg Arnold, DC, CSCS, July 7, 2006, abstracted from “Inhibitory effects of cranberry polyphenols on formation and acidogenicity of Streptococcus mutans biofilms” in the April 2006 issue of FEMS Microbiology Letters Despite making 500 million visits to dentists and spending an estimated $84 billion on dental services in 2005, cavities affect one in four American children aged 2–5 and half of those aged 12–15. Cavities and tooth decay is also a serious problem in adults, with 90% of adults over 40 years of age having cavities and one in four adults over age 60 years having lost all of their teeth. Finally, cavities and tooth decay are precursors to oral cancer, which causes more than 7,000 deaths each year.(1) When looking at the mechanism behind cavities and tooth decay, research has identified the bacteria Streptococcus mutans as the primary bacterium in helping cause cavities.(2) Now a new study(3) has found that helping decrease levels of this cavity-causing bacterium may be decreased by increasing your intake of cranberries . As a widely consumed fruit in North America, American cranberry has been found to provide a number of human health benefits(4) including helping protect against urinary tract infections (5) and peptic ulcers .(6) It is believed that the high levels of antioxidants called phenolic acids, anthocyanins and flavonols in cranberries are what constitute its’ health promoting benefits.(7) In the study, researchers used four different preparations of cranberry extract (20 mg) found in most commercial cranberry products. Seasonal variations result in different antioxidant contents of cranberries so the researchers used flavonol (30-125 micrograms per milliliter), anthocyanin (50-200 micrograms), and proanthocyanidin (PAC) (300-500 micrograms) rich samples. They exposed these four extracts to streptococcus mutans and observed their effect on two enzymes called GTF and F-ATPase. GTF is the primary enzyme used by streptococcus mutans to help cause cavities(8) and F-ATPase has been found to prevent acidity and accelerate cavity formation.(9) The researchers found that the flavonoid and proanthocyanidin-rich cranberry extracts, alone or in combination, “significantly inhibited” the activities of GTF by as much has 60% and F-ATPase by as much as 85%. For the researchers, this study has “shown clearly the potential of cranberry flavonols and proanthocyanidins to interfere with…S. mutans [activity]” and may be a very effective way to help protect against cavities. Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com Reference: 1 Oral Health: Preventing Cavities, Gum Disease, and Tooth Loss – At A Glance 2006” posted on the CDC website www.cdc.gov/nccdphp/publications/aag/oh.htm 2 Beighton D (2005) The complex oral microflora of high-risk individuals and groups and its role in the caries process. Community Dent Oral Epidemiol 33: 248–255 3 Duarte S. Inhibitory effects of cranberry polyphenols on formation and acidogenicity of Streptococcus mutans biofilms. FEMS Microbiol Lett 2006; 257(1): 50-57 4 Ahuja S, Kaack B & Roberts J (1998) Loss of fimbrial adhesion with the addition of Vaccinium macrocarpon to the growth medium of P-fimbriated Escherichia coli. J Urol 159: 599–562 5 Stothers L. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women. Can J Urol 2002; 9: 1558 62 6 Lian Zhang, J. Efficacy of Cranberry Juice on Helicobacter pylori Infection: a Double-Blind, Randomized Placebo-Controlled Trial. Helicobacter 2005; 10(2): 139-145 7 Cunningham DE, Vannozzi SA, Turk R, Roderick R, O'Shea E & Brilliant K (2004) Cranberry phytochemicals and their health benefits. Nutraceutical Beverages: Chemistry, Nutrition, and Health Effects. ACS Symposium Series 871 (Shahidi F & Weerasinghe DK, eds), pp. 35–50. American Chemical Society, Washington, DC. 8 Bowen WH (2002) Do we need to be concerned about dental caries in the coming millennium? Crit Rev Oral Biol Med 13: 126–131 9 Quivey RG Jr, Faustoferri R, Monakan K & Marquis R (2000) Shifts in membrane fatty acid profiles associated with acid adaptation of Streptococcus mutans. FEMS Microbiol Lett 189: 89–92.

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Study Finds Vitamin C and E Deficiencies Cause Nervous System Damage By Greg Arnold, DC, CSCS, June 6, 2006, abstracted from "Combined Deficiency of Vitamins E and C Causes Severe Central Nervous System Damage in Guinea Pigs" in the June 2006 issue of the Journal of Nutrition For more than three decades, science has tried to uncover the role antioxidants play in health, which include helping neutralize free radicals1 and helping fight cancer.2 Recent research has found that two particular antioxidants, vitamin C and vitamin E , play pivotal roles in our health, by helping prevent blindness in the elderly,(3) helping protect against prostate cancer ,(4) helping decrease inflammation ,(5) treat gout ,(6) stabilize irregular heartbeats ,(7) and even providing an alternative to chemotherapy.(8) Now a new study(9) has found that deficiencies in these two vitamins cause disease by inflicting considerable harm on our nervous system. In the study, researchers fed four different group of guinea pigs a diet either deficient in vitamin E, absent of vitamin E, deficient in vitamin C or deficient of both vitamins for two weeks. While very little change was seen in the single-vitamin deficiency groups, 9 of the 12 guinea pigs in the combined deficiency group developed paralysis and two more died between days 5 and 11 of the study. Only one of the guinea pigs in the combined deficiency group survived without any impairment until day 14. When examining the guinea pigs, the researchers found that only the combined deficiency produced damage in the nervous systems of the guinea pigs. The damage was most severe at the base of the brain and the spinal cord and consisted mainly of nerve cell death, nerve cell degeneration and blood vessel injury. For the researchers, "The…paralysis and death caused by combined deficiency of vitamins E and C in guinea pigs is caused by severe damage in the brainstem and spinal cord." Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com Reference: 1 Kent S. Do free radicals and dietary antioxidants wage intracellular war? Geriatrics. 1977 Jan;32(1):127-36. 2 Talalay P. Biochemical studies on the mechanisms by which dietary antioxidants suppress mutagenic activity. Adv Enzyme Regul. 1978;17:23-36. 3 Van Leeuwen. Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA. 2005 Dec 28;294(24):3101-7 4 Jiang, Q., J. Wong, et al. (2004). "[gamma]-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis." Proc Natl Acad Sci U S A 101(51): 17825-17830 5 Wang, X.L., et al., Cosupplementation with vitamin E and coenzyme Q10 reduces circulating markers of inflammation in baboons. Am J Clin Nutr, 2004. 80(3): p. 649-55 6 Huang, H. Y., L. J. Appel, et al. (2005). "The effects of vitamin C supplementation on serum concentrations of uric acid: results of a randomized controlled trial." Arthritis Rheum 52(6): 1843-7 7 Korantzopoulos, P., T. M. Kolettis, et al. (2005). "Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation." Int J Cardiol 102(2): 321-6 8 Sebastian J. Intravenously administered vitamin C as cancer therapy: three cases. CMAJ 2006 174: 937-942 9 Burk RF. A Combined Deficiency of Vitamins E and C Causes Severe Central Nervous System Damage in Guinea Pigs. Jou Nutr 2006; 136: 1576-1581

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Magnesium Found to Possibly Play a Protective Role Against Asthma By Greg Arnold, DC, CSCS, July 9, 2006, abstracted from “Oral magnesium supplementation in asthmatic children: a double-blind randomized placebo-controlled trial” printed online June 21, 2006 in the European Journal of Clinical Nutrition Magnesium is a mineral with an abundance of health benefits including helping protect against type 2 diabetes ,(1) regulating blood pressure,(2) increasing HDL cholesterol(3) and helping protect against Syndrome X *.(4) Magnesium is naturally obtained from whole seeds, grains, nuts and vegetables but is mostly lost after food processing.(5) This loss is reflected in recent research showing that magnesium intake before the industrial revolution was 475–500 mg per day(6) but it has “declined substantially” during the 20th century and now stands between 280 and 350 mg per day.(7) This decline in magnesium intake is believed to contribute to the “dramatic increase” in asthma over the last 50 years.(8) Now, building upon previous research showing that low magnesium intake is associated with airway hyper-reactivity(9) and self-reported wheezing(10) and that decreased antioxidant intake increases asthma risk,(11) a new study(12) has found that magnesium may play a role in helping protect against asthma. In the study, patients with persistent asthma received either 300 mg per day of magnesium (18 patients) or placebo (19 patients) for two months. During this time, they were allowed to take the asthma medications fluticasone and salbutamol, as needed. The researchers used lung reactivity, evaluated by using a methacholine challenge test, as the primary outcome measure. At the end of two months, the researchers found that lung reactivity was “[decreased] significantly in the magnesium group only” and that allergic skin reactions also decreased in the magnesium group compared to the placebo. Finally, the magnesium group had fewer asthma exacerbations and used less of the medications compared to the placebo group. For the researchers, “Oral magnesium supplementation helped to reduce [lung] reactivity, to diminish their [allergic] skin [reactions] and to provide better symptom control in pediatric patients with moderate persistent asthma treated with inhaled fluticasone.” *Syndrome X is a cluster of metabolic abnormalities, including insulin resistance, high blood levels of triglycerides, low blood levels of HDL-cholesterol, and obesity, that increase the risk of chronic diseases such as hypertension, coronary artery disease, and diabetes (from The American Heritage® Stedman's Medical Dictionary, 2nd Edition Copyright © 2004 by Houghton Mifflin Company. Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com Reference: 1 Hu FB. Magnesium intake and risk of type 2 diabetes in men and women. Diabetes Care. 2004;27:134–140 2 Klag MJ. The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials. Am J Hypertens. 2002;15:691–696 3 Kulshretha SK. Can dietary magnesium modulate lipoprotein metabolism? Magnes Trace Elem. 1990;9:255–264 4 Furukawa, S., T. Fujita, et al. (2004). "Increased oxidative stress in obesity and its impact on metabolic syndrome." J Clin Invest 114(12): 1752-61 5 National Research Council (US) (1989). Recommended Dietary Allowances, 10th edn. National Academy Press: Washington, DC. 6 Altura BM, Altura BT (1991–92). Cardiovascular risk factors and magnesium relationships to atherosclerosis, ischemic heart disease and hypertension. Magnesium Trace Elem 10, 182–192 7 USDA (1990). Continuing Survey of Food Intake by Individuals 1989 and 1990. USDA Public Use Data Tape USDA: Washington, DC. 8 Chadwick DJ, Cardew C (eds) (1997). The Rising Trends in Asthma, CIBA Foundation Symposium No. 206. Wiley: New York. 9 Britton J et al. (1994). Dietary magnesium, lung function, wheezing and airway hyperreactivity in a random adult population sample. Lancet 344, 357–362 10 Soutar A, Seaton A, Brown K (1997). Bronchial reactivity and dietary antioxidants. Thorax 52, 166–170. 11 Patel BD. Dietary antioxidants and asthma in adults. Thorax, May 2006; 61; 388 - 393.

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Milk Thistle Provides Hope in Protecting Against Lung Cancer By Greg Arnold, DC, CSCS, July 11, 2006, abstracted from "Effect of Silibinin on the Growth and Progression of Primary Lung Tumors in Mice" in the June 2006 issue of the Journal of the National Cancer Institute As a cancer that causes one in three cancer-related deaths each year, has a "dismal" 5-year survival rate of approximately 14% and has shown no improvement over the past 30 years,(1) lung cancer is expected to cause 10 million deaths per year worldwide by the year 2030.(2) While stopping smoking and minimizing radon exposure(3) are the most advocated methods of reducing lung cancer risk, research on foods as a preventive measure is sparse, with recent research finding that pomegranates (4) offer protection against lung cancer. Now a new study(5) has found that milk thistle , known primarily for liver health,(6) may also offer protection against lung cancer. In the study, researchers injected 75 mice with a solution of urethane (1 mg per g body weight), which has been found to stimulate lung cancer development.(7) They injected 15 mice with saline to serve as controls. All mice were fed a control diet for two weeks after injection. The 75 urethane-injected mice were either kept on the control diet or given diets that contained silibinin, an antioxidant in milk thistle,(8) in the amounts of 033%, 0.10%, 0.33%, or 1.0% of the mouse bodyweight. The lung tumors of the mice given urethane were then examined at 20 and 29 weeks after injection. The researchers found that the urethane-injected mice in the silibinin group "had statistically significantly lower" incidence of lung tumors after 20 weeks compared to the urethane group not given silibinin. This same result was also found in the mice after 29 weeks. Specifically, the researchers focused on how milk thistle restricts blood supply to tumors and restricts tumor growth.(9) Specifically, the dose of 1% silibinin reduced large tumors by 93% compared to controls. For the researchers, the results of this study "merit investigation [for milk thistle] as a chemopreventive agent for suppressing lung cancer progression." Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com Reference: 1 Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10-30 2 Proctor RN. Tobacco and the global lung cancer epidemic. Nat Rev Cancer 2001;1:82-6. 3 Surgeon General Releases National Health Advisory On Radon" posted January 13, 2005 on the Health and Human Services Website www.surgeongeneral.gov/pressreleases/sg01132005.html 4 Khan N. Modulation of MAPK and NF-êB pathways in human A549 lung carcinoma cells by pomegranate fruit extract. Abstract # 3193 presented at the 97th Annual AACR Conference April 1-5, 2006 5 Singh RP. Effect of Silibinin on the Growth and Progression of Primary Lung Tumors in Mice. J Natl Cancer Inst 2006; 98: 846-855 6 "Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects" posted on the Agency for Healthcare Research Quality Website www.ahrq.gov/clinic/epcsums/milktsum.htm 7 Malkinson AM. Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung. Lung Cancer 2001;32:265-79 8 Wellington K, Jarvis B. Silymarin: a review of its clinical properties in the management of hepatic disorders. BioDrugs 2001;15:465-89 9 Gimbrone MA Jr, Leapman SB, Cotran RS, Folkman J. Tumor dormancy in vivo by prevention of neovascularization. J Exp Med 1972;136:261-76 Check out all of our new products Herbal Remedies has added to our wide variety of natural health products! Do you have a question for us? If so please send in your questions to herbalnews@qwest.net We will answer all email ASAP!

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For assistance or to purchase products by phone call toll free in the USA 1-866-467- 6444 or World Wide 1-307-577-6444 or e-mail your questions to herbalnews@qwest.net. We will answer e-mails in the newsletter as space allows. Our Sponsors HerbalRemedies.com Get the finest all natural health products, get the best service, and low cost worldwide delivery. Enter coupon code "NL072406" when checking out to obtain discounts on your next purchase from www.HerbalRemedies.com