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Herbal Remedies Natural Health Newsletter, January 2009, Issue 287 Home > Feedback / Testimonials / Archives > Newsletter Archives >
Herbal Remedies January 2009 Natural Health Newsletter Issue 287 Sponsored by www.HerbalRemedies.com Toll Free for orders 1-866-467-6444
Issue Editor -
Heather Bowman
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Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books
- Vitamin E Found to Benefit Lung Health
- Click here for full story.
- CoQ10 Found to Play a Role in Mental Health - Click here for full story.
- Melatonin Found to Help Cholesterol Health
- Click here for full story.
- Alpha-Linolenic Acid (ALA) Found to Reduce Risk of Heart Attack
- Click here for full story.
- Green Tea Improves Detoxification
- Click here for full story.
Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies
Be sure to check out our Overstocked clearance items! OVERSTOCKED Give your skin a natural glow with Burt's Bees Products. We are your #1 Headquarters for your complete line of Burt’s Bees Products for that all around natural glow!!
Herbal Remedies has four new vendors be sure to check them out: Twinlab Fuel Supplements , Boiron Homeopathy, Qmelt , and Naturally Vitamins Products Spotlight –HOW DO I LOVE THEE? LET ME SHOW YOU THE WAYS! Valentine's Day is just around the corner, are you ready to show your partner how much you care now and throughout the year, thanks to some helpful aphrodisiacs we can help spice up your nights! We are your Headquarters for a complete line of Herbal Aphrodisiacs this Valentine’s Day! Current Event News: Are you prepared for your New Year’s Resolution? Get a Jumpstart on Your New Years Resolution with a little help from a friend, Herbal Remedies! Every year numerous people make New Year’s resolutions only to feel let down when they find it next to impossible to keep them. In fact, most resolutions will be broken before February 1. Easy to do considering that the top three most popular resolutions are all behavior modifications: lose weight, quit smoking and exercise. Well, Herbal Remedies has the answers to achieving these goals without the harmful side effects of chemical abuse. The exercise is all on you, although we can help you get the energy you need to sustain your workout naturally. The Stroke of Midnight won’t be a problem with Herbal Remedies!
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QUESTIONS AND ANSWERS
Q:
Subject: Hello Is there any treatment or help for multiple sclorises.Age 29 suffering three years. Is there any known help or any herbs,vitamins etc.my friend has son who is the victim of this. Please help.
Thank you for your time.
A:
Dear Customer, Dear Customer,
Multiple Sclerosis is an immune system disorder that causes the body’s own antibodies to attack the myelin sheath in the brain and the spinal cord, causing inflammation and scaring. There are three products you may want to try taking to begin feeling some relief from MS: First Lecithin Concentrate is the most abundant phospholipid serving as a structural material for every cell in the body and is an essential constituent of the brain and nervous system responsible for breaking down cholesterol, transporting fats, rebuilding organs, maintaining organ, cardiovascular, and endocrine health, fights infections, lowers blood pressure, restores sexual energy, eases PMS and menopausal tension, promotes energy and benefits nervous and mental disorders. Then Vitamin B Complex supports the nervous system and the immune system. Last but not least MSM helps build new cells and supports the removal of waste and toxins. In order to maintain overall health changing diet would be suggested. There is a lower occurrence of multiple sclerosis in countries where diets low in fats and rich in fatty acids, such as Omega 3 fatty acids from sea foods, seeds and fruits, which may have an inhibitory affect on the inflammatory symptoms of the disease.
Thank you and All my best,
Thank you for your interest in Herbal Remedies.com and the opportunity to serve you.
Heather
* The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products.
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Vitamin E Found to Benefit Lung Health
By Greg Arnold, DC, CSCS, November 3, 2008, abstracted form “Dietary alpha-, beta-, gamma- and delta-tocopherols in lung cancer risk” in the September 1, 2008 issue of the International Journal of Cancer
As the leading cancer killer in men and women, lung Alzheimer Disease cancer affects an estimated 350,679 Americans(1), costs our health care system $9.6 billion per year(2), and causes more deaths than the next three most common cancers combined (colon, breast and prostate). While the five-year survival rate for colon, breast, and prostate cancer patients is 63%, 88%, and 99%, respectively, it is only 15% for lung cancer patients(3).
Natural ways to help maintain lung health include fiber (4), pomegranates (5), flaxseed (6), zinc (7), choline (8), milk thistle (9), and flavonoids in both smokers (10) and postmenopausal women(11). Now a new study(12) has found that vitamin E , known to help with mental health (13), heart health(14), eye health (15), children’s health(16), and prostate health (17), may also help with lung health. In the study, 1,088 patients diagnosed with lung cancer and 1,414 patients without lung cancer provided data on their diet by completing a 135-item National Cancer Institute's Health Habits and History Questionnaire (HHHQ), used successfully in previous research(18).
The researchers found that those with the highest intake of the form of vitamin E called tocopherols (more than 12.95 mg per day) had a 55% reduced risk of lung cancer compared to those with the lowest intake (less than 6.68 mg per day). When looking at specific tocopherols, researchers found 61% risk reduction for alpha tocopherol (more than 7.73 mg per day compared to less than 4.13), 44% reduced risk for beta-tocopherol (more than 0.08 mg per day compared to less than 0.04), 44% reduced risk for gamma-tocopherol (more than 4.44 mg per day compared to less than 1.83 mg per day) and 19% reduced risk for delta tocopherol (0.78 mg per day compared to less than 0.28 mg per day).
For the researchers, “To the best of our knowledge, this is the first report of the independent associations of the 4 forms of dietary tocopherol (alpha-, beta-, gamma- and delta-tocohperol) on lung cancer risk.”
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at http://www.completechiropractichealthcare.com/
Reference:
1 Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Mariotto A, Feuer EJ, Edwards BK (eds). SEER Cancer Statistics Review, 1975-2002, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2002/
2 “Cost of Lung Cancer” posted on www.cdc.gov/cancer/lung/statistics/cost.htm
3 "Lung Cancer Fact Sheet" posted on the American Lung Association Website www.lungusa.org
4 Kan H. Dietary Fiber, Lung Function, and Chronic Obstructive Pulmonary Disease in the Atherosclerosis Risk in Communities Study. American Journal of Epidemiology Advance Access published on December 5, 2007. doi:10.1093/aje/kwm343
5 Khan N. Modulation of MAPK and NF-êB pathways in human A549 lung carcinoma cells by pomegranate fruit extract. Abstract # 3193 presented at the 97th Annual AACR Conference April 1-5, 2006
6 Bloedon LT. Flaxseed and cardiovascular risk. Nutr Rev. 2004 Jan;62(1):18-27
7 Meydani SN. Am. J. Clinical Nutrition, Oct 2007; 86: 1167 – 1173
8 Sheila M Innis. Choline-related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis Am. J. Clinical Nutrition, Mar 2007; 85: 702 – 708
9 Singh RP. Effect of Silibinin on the Growth and Progression of Primary Lung Tumors in Mice. J Natl Cancer Inst 2006; 98: 846-855
10 Cui Y. "Dietary flavonoid intake and lung cancer - a population-based case-control study". Cancer 2008; 112(10): 2241-2248
11 Cutler GJ. Dietary flavonoid intake and risk of cancer in postmenopausal women: The Iowa Women's Health Study. Int Jou Cancer 2008; 123(3): 664-671 Published Online: May 19 2008 3:15PM DOI: 10.1002/ijc.23564
12 Mahabir S. Dietary alph-, beta-, gamma- and delta-tocopherols in lung cancer risk. Int J Cancer 2008; 123(5): 1173-1180. Published Online: Jun 10 2008 2:32PM OI: 10.1002/ijc.23649
13 American Academy of Neurology 60th Anniversary Annual Meeting 15 April 2008, Poster Sessions III: Aging and Dementia: Clinical II [P03.076] Vitamin E Use Is Associated with Improved Survival in an AD Cohort Authors: V. Pavlik, R. Doody, S. Rountree, E. Darby
14 Das S. Cardioprotection with palm oil tocotrienols: comparision of different isomers. Am J Physiol Heart Circ Physiol 2008; 294:H970-H978
15 Nourmohammadi I. Association of Serum alpha-Tocopherol, Retinol and Ascorbic Acid with the Risk of Cataract Development. Ann Nutr Metab 2008;52:296-298 (DOI:10.1159/000148189)
16 Beyrouty P. Co-consumption of selenium and vitamin E altered the reproductive and developmental toxicity of methylmercury in rats Neurotoxicity and Teratology. Available online 19 January 2006
17 Spaccarotella KJ. The effect of walnut intake on factors related to prostate and vascular health in older men. Nutr J 2008;7:13
18 Block G,Coyle LM,Hartman AM. Scoppa SM. Revision of dietary analysis softwarre for the health habits and history questionnaire. Am J Epidemiol 1994; 139: 1190-6
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CoQ10 Found to Play a Role in Mental Health
By Greg Arnold, DC, CSCS, October 30, 2008, abstracted from “The coenzyme Q10 status of the brain regions of Parkinson’s disease patients” in the December 2008 issue of Neuroscience Letters
Parkinson’s Disease (PD) is characterized by tremors, slowness of movement, stiffness, and difficulty with balance. The condition affects more than 1.5 million Americans, with 60,000 new cases each year(1). The combined direct and indirect costs of PD are estimated at more than $5.6 billion per year in the U.S. With medication costs for an individual patient averaging $2,500 a year, and therapeutic surgery costing up to $100,000 dollars per patient(2), prevention of PD is a priority.
Vitamin B-6 (3), green tea (4), unsaturated fat and vitamin E (5), and losing weight (6) have been shown to help maintain mental health . Now a new study(7) has found that Coenzyme Q10 may benefit mental health and PD. CoQ10 is also known to help with blood sugar health(8), heart health(9), fatigue(10), healthy inflammation levels(11), headaches (12), women’s health(13) and Alzheimer Disease (14).
In the study, researchers compared 25 healthy brains to 25 PD brains for CoQ10 levels. Those with PD were diagnosed at an average age of 61 years, resulting in death at an average age of 75. Using a process called High Performance Liquid Chromatography(15), the researchers looked at four different areas of the brain. They found only one region, the cortex (which is involved with complex tasks), that “showed a significant decrease in CoQ10 levels in PD [samples] compared to controls” with a difference of 87.3 picomoles per mg.
The exact cause of the Co10 decrease in the brain cortex is not known. But the researchers speculated that CoQ10 deficiency in the brain may “impair…energy metabolism resulting in increased free radical production and oxidative stress” through dysfunction of the process that produces energy in our cells called the Electron Transport Chain (ETC)(16) of which CoQ10 plays a very important role.
And although previous studies have reported reduced CoQ10 levels in blood(17) and in the cells(18) of PD patients, this was the first study to prove CoQ10 deficiencies in actual human brain tissue. For the researchers, “the evidence of decreased brain CoQ10 [levels]…is therefore consistent with the reported [supplementation] of CoQ10 supplementation in the retardation of…deterioration in early stage PD.”
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com
Reference:
1 “About Parkinson Disease” posted on the National Parkinson Foundation Website www.parkinson.org
2 “Ten Frequently Asked Questions About Parkinson’s Disease” posted on the Parkinson’s Disease Foundation Website www.pdf.org/
3 de Lau LM. Dietary folate, vitamin B12, and vitamin B6 and the risk of Parkinson disease. Neurology. 2006 Jul 25;67(2):315-8
4 Guo. S. Protective Effects of Green Tea Polyphenols in the 6-OHDA Rat Model of Parkinson’s Disease Through Inhibition of ROS-NO Pathway. Biol Psych 2007; 62(12):1353-1362
5 Miller ER 3rd. Meta-analysis: High-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005; 142: 37-46
6 Whitmer, R. A., E. P. Gunderson, et al. (2005). "Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study." www.bmj.com
7 Hargreaves IP. The coenzyme Q10 status of the brain regions of Parkinson’s disease patients. Neuroscience Letters 447 (2008) 17–19
8 Petersen, K. F., D. Befroy, et al. (2003). "Mitochondrial dysfunction in the elderly: possible role in insulin resistance." Science 300(5622): 1140-2
9 Tiano L. Effect of coenzyme Q10 administration on endothelial function and extracellular superoxide dismutase in patients with ischaemic heart disease: a double-blind, randomized controlled study. European Heart Journal Advance Access published on July 19, 2007. doi:10.1093/eurheartj/ehm267
10 Mizuno K. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition 2008; 24(4): 293-299
11 Wang, X.L., et al., Cosupplementation with vitamin E and coenzyme Q10 reduces circulating markers of inflammation in baboons. Am J Clin Nutr, 2004. 80(3): p. 649-55
12 Pothmann, R. Migraine Prevention in Children and Adolescents: Results of an Open Study With a Special Butterbur Root Extract. Headache 2005; 45(3): 196-203
13 Palan PR. Effects of menstrual cycle and oral contraceptive use on serum levels of lipid-soluble antioxidants. Am Jou Obst Gyn 2006; 194(5): e35-e38
14 Ishrat T. Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats. Printed online in Behavioural Brain Research doi:10.1016/j.bbr.2006.03.009
15 Explanation of HPLC available at www.pharm.uky.edu/ASRG/HPLC/HPLCMYTRY.html
16 Video Demonstration available at www.youtube.com/watch?v=Idy2XAlZIVA
17 T. Matsubara, T. Azums S. Yoshids, T. Yamegami, Serum coenzyme Q-10 level in Parkinson syndrome, in: K. Folkers, G.P. Littarru, T. Yamagami (Eds.), Biomedical and Clinical Aspects of Coenzyme Q, vol. 16, Elsevier Science, Amsterdam, 1991, 159–166
18 C.W. Shults, R.H. Haas, D. Passor, M.F. Beal, Coenzyme Q10 levels is reduced in mitochondria from Parkinsonian patients, Ann. Neurol. 42 (1997) 61–65
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Melatonin Found to Help Cholesterol Health
By Greg Arnold, DC, CSCS, March 7, 2008, abstracted from “Melatonin treatment in peri- and postmenopausal women elevates serum high-density lipoprotein cholesterol levels without influencing total” printed online in the Journal of Pineal Research February 19, 2008
Melatonin is produced by the pineal gland that resides in the brain. It helps increase sleep quality by regulating the circadian rhythm (our body’s biological clock)(1) and helping reduce inflammation (2). One recent study even found that melatonin helps maintain normal brain development in children(3).
Melatonin has been found to be associated with a number of health benefits, including helping reduce ringing in the ears(4), lung health (5) and even heart health in women(6). Now a new study(7) has found that melatonin also benefits women’s heart health because of its ability to maintain healthy HDL cholesterol levels.
In the two-part study, 36 women aged 30-73 years provided blood samples at 2 a.m. to measure melatonin levels. Another blood sample was drawn at 9 a.m. to measure cholesterol and triglyceride levels. In the second part of the study, 10 peri- and postmenopausal women aged 42-65 years were given 1 mg per day of melatonin for one month. During this time, they gave blood samples to measure cholesterol and triglyceride levels.
The first part of the study showed that melatonin levels had a positive correlation with HDL cholesterol levels, while having negative correlations with both total cholesterol and LDL cholesterol. In the second part of the study, the researchers found that 1 mg of melatonin per day increased HDL cholesterol by 29% (51.3 mg/dL to 66.1 mg/dL) with no significant changes in either LDL cholesterol (110.9 to 113.6)) or triglycerides (135.4 to 139.1)).
For the researchers, “melatonin administration may become a new medical application for the improvement of lipid metabolism and prevention of cardiovascular disease in peri- and postmenopausal women.”
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.completechiropractichealthcare.com.
Reference:
1 Rajaratnam, S. M., B. Middleton, et al. Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunities. J Physiol 2004
2 Cuzzocrea, S. and R. J. Reiter (2002). "Pharmacological actions of melatonin in acute and chronic inflammation." Curr Top Med Chem; 2(2): 153-65
3 Smits, M. G., H. F. van Stel, et al. (2003). "Melatonin improves health status and sleep in children with idiopathic chronic sleep-onset insomnia: a randomized placebo-controlled trial." J Am Acad Child Adolesc Psychiatry 42(11): 1286-93
4 Uchechukwu C. The Effects of Melatonin on Tinnitus and Sleep. Otolaryngology: Head and Neck Surgery 2006; 134(2): 210-213
5 Francineide L. Campos, Francisco P. da Silva-Júnior, Veralice M. S. de Bruin, and Pedro F. C. de Bruin Melatonin Improves Sleep in Asthma: A Randomized, Double-blind, Placebo-controlled Study. Am. J. Respir. Crit. Care Med. 2004; 170: 947-951
6 Tamura M. Melatonin treatment in peri- and postmenopausal women elevates serum high-density lipoprotein cholesterol levels without influencing total. Jou Pineal Res 2008. Published article online doi: 10.1111/j.1600-079X.2008.00561.x
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Alpha-Linolenic Acid (ALA) Found to Reduce Risk of Heart Attack
By Greg Arnold, DC, CSCS, August 5, 2008, abstracted from “alpha-Linolenic Acid and Risk of Nonfatal Acute Myocardial Infarction” in the July 22, 2008 issue of Circulation
According to the American Heart Association, heart attacks caused 451,326 deaths in 2004 (1 of every 5 deaths) with 1.2 million new or repeat heart attacks occurring every year. More than 16 million Americans currently suffer from angina (chest pain due to coronary heart disease) or have had a heart attack(1). Finally, about 7.9 million Americans aged 20 and older have survived a heart attack(2).
Vitamin D (3) and beta-carotene (4) have been shown to help maintain heart health. A recent study(5) has found that alpha-linolenic acid (ALA) may be a viable alternative to fish oils (6) in reducing the risk of heart attack. ALA is an omega-3 fatty acid found in vegetable cooking oils such as soybean and canola oils, and other products of plant origin.
In the study, over 1800 patients living in Costa Rica completed a 135-item food questionnaire(7), providing information on their fatty acid intake from Costa Rican food staples, including rice, beans, bread, plantains, and eggs. They also completed a questionnaire on their physical activity(8) and provided tissue samples that were measured for have fatty acid levels.
The researchers found that compared to those with the lowest intake of ALA (1 gram per day), those with the highest intake of ALA (2.7 grams per day) had a 39% reduced risk of a heart attack. Because ALA has been suggested to be a replacement for fish oil , the researchers looked at whether ALA in those with low fish intake still had reduced risks of a heart attack. They found that those in the highest one-third of ALA intake had a 50% lower heart attack risk among those with the lowest fish intake (3.3 grams of fish per day), a 52% lower risk among those in the middle one-third of fish intake (13.4 grams of fish per day), and a 55% lower risk among those with the highest fish intake (32.4 grams per day).
These results are confirmed by previous research(9) showing the protective effect of a Mediterranean diet rich in ALA against the risk of heart attack. They also suggest the anti-inflammatory properties of ALA as a reason for this protective effect(10, 11) though this has been doubted in other research(12, 13). For the researchers, “it is possible that consumption of vegetable oils rich in alpha-linolenic acid could confer important cardiovascular protection in many countries where intake is low.”
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com
Reference:
1 “Heart Attack and Angina Statistics” posted on www.americanheart.org/presenter.jhtml?identifier=4591
2 “Know the Facts: 2007” posted on www.americanheart.org/downloadable/heart/116861545709855-1041%20KnowTheFactsStats07_loRes.pdf
3 Giovanucci E. 25-Hydroxyvitamin D and Risk of Myocardial Infarction in Men: A Prospective Study. Arch Intern Med. 2008;168(11):1174-1180
4 Furtado J. Some dietary and adipose tissue carotenoids are associated with the risk of nonfatal acute myocardial infarction in Costa Rica. J Nutr. 2005 Jul;135(7) :1763-9
5 Campos H. Alpha-Linolenic Acid and Risk of Nonfatal Acute Myocardial Infarction. Circulation. 2008;118:339-345; published online before print July 7 2008, doi:10.1161/CIRCULATIONAHA.107.762419
6 Harris WS. Alpha-linolenic acid: a gift from the land? Circulation. 2005; 111: 2872–2874
7 Kabagambe EK, Baylin A, Allan DA, Siles X, Spiegelman D, Campos H. Application of the method of triads to evaluate the performance of food frequency questionnaires and biomarkers as indicators of long-term dietary intake. Am J Epidemiol. 2001; 154: 1126–1135
8 Campos H, Siles X. Siesta and the risk of coronary heart disease: results from a population-based, case-control study in Costa Rica. Int J Epidemiol. 2000; 29: 429–437
9 de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation. 1999; 99: 779–785
10 Ferrucci L, Cherubini A, Bandinelli S, Bartali B, Corsi A, Lauretani F, Martin A, Andres-Lacueva C, Senin U, Guralnik JM. Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab. 2006; 91: 439–446
11 Lopez-Garcia E, Schulze MB, Manson JE, Meigs JB, Albert CM, Rifai N, Willett WC, Hu FB. Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women. J Nutr. 2004; 134: 1806–1811
12 Pischon T, Hankinson SE, Hotamisligil GS, Rifai N, Willett WC, Rimm EB. Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women. Circulation. 2003; 108: 155–160
13 Goyens PL, Spilker ME, Zock PL, Katan MB, Mensink RP. Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio. Am J Clin Nutr. 2006; 84: 44–53
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Green Tea Improves Detoxification
By Greg Arnold, DC, CSCS, March 11, 2008, abstracted from “Modulation of Human Glutathione S-Transferases by Polyphenon E Intervention" in the August 1, 2007 issue of Cancer Epidemiology Biomarkers and Prevention
The American Cancer Society estimates that almost 566,000 Americans will die of cancer in 2008, more than 1,500 people per day. In 2007, cancer cost our healthcare system over $219 billion. Fortunately, 5-year survival rates for cancer from 1996 through 2003 was 66%, up from 50% in 1975-1977, reflecting “progress in diagnosing certain cancers at an earlier stage and improvements in treatment”(1).
When looking at what helps maintain overall cellular health, detoxification in the form of metabolizing (breaking down) and eliminating substances called xenobiotics (e.g.drugs and carcinogens) is vital to our health. The metabolizing of these xenobiotics comes in several phases in the body, called Phase I and Phase 2 metabolism. Regarding Phase 2 metabolism, an important group of enzymes called glutathione S-transferases (GSTs) are a core component of helping eliminate xenobiotics and detoxify the body. GSTs are so important that previous research has found that people deficient in GSTs are at increased risk of cancer due to the lack of detoxification(2, 3).
Now a new study(4) has found that green tea polyphenols , found previously to help with prostate health (5), and oral health(6) as well as colon(7), stomach(8), lung(9) and ovary health(10), may help with detoxification by improving GST activity.
The study participants were 42 non-smoking men and women over 18 years of age with normal liver and kidney function. They were given green tea extract that provided 800 mg of EGCG , the primary antioxidant in green tea, on an empty stomach daily for four weeks. During this time, they kept a diary to document any side effects and they also had blood samples taken. The 800 mg of EGCG was taken on empty stomach because research has shown its absorption to be much better versus taking it with meals(11).
The researchers found that those with the lowest GST activity levels before the study began had an 80% increase in GST activity by the end of the study. Those with the highest GST levels initially had no improvements in GST activity. For the researchers, “This suggests that green tea polyphenol intervention may enhance the detoxification of carcinogens in individuals with low baseline detoxification capacity.”
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com
Reference:
1 “Cancer Facts & Figures 2008: posted on www.cancer.org/downloads/STT/2008CAFFfinalsecured.pdf
2 Nelson W, Deweese T, De Marzo A. The diet, prostate inflammation, and the development of prostate cancer. Cancer Metastasis Rev 2002;21:3–16
3 Grubben MJ, Nagengast FM, Katan MB, Peters WH. The glutathione biotransformation system and colorectal cancer risk in humans. Scand J Gastroenterol 2001;234S:68–76
4 Chow, H; Hakim, I; et al. Modulation of Human Glutathione S-Transferases by Polyphenon E Intervention, Cancer Epidemiology Biomarkers and Prevention, 16, 1662-1666, August 1, 2007
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