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Herbal Remedies Natural Health Newsletter, February 2009, Issue 288

Herbal Remedies February 2009 Natural Health Newsletter Issue 288 Sponsored by www.HerbalRemedies.com Toll Free for orders 1-866-467-6444 Issue Editor - Heather Bowman

Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books Melatonin May Help Eye Health - Click here for full story. Vitamin D Deficiency May Carry Long-Term Disease Risks - Click here for full story. Broccoli Compound Shown to Benefit Breast Cell Health - Click here for full story. Fish Oil Component Found Helpful for Lung Health - Click here for full story. Study Finds Hypertension Medications May Cause Diabetes by Depleting Potassium Levels - Click here for full story. Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies Be sure to check out our Overstocked clearance items! OVERSTOCKED Give your skin a natural glow with Burt's Bees Products. We are your #1 Headquarters for your complete line of Burt’s Bees Products for that all around natural glow!! Herbal Remedies has four new vendors be sure to check them out: Twinlab Fuel Supplements , Boiron Homeopathy, Enzymatic Therapy , and Naturally Vitamins Products Spotlight –HOW DO I LOVE THEE? Don’t Stop Showing Your Partner The Ways! Just because Valentine’s Day is over doesn’t mean you can’t show your partner how much you care now and throughout the year, thanks to some helpful aphrodisiacs we can help spice up your nights! We are your Headquarters for a complete line of Herbal Aphrodisiacs for the month of love! Current Event News: Are you prepared for your New Year’s Resolution? Get a Jumpstart on Your New Years Resolution with a little help from a friend, Herbal Remedies! Every year numerous people make New Year’s resolutions only to feel let down when they find it next to impossible to keep them. In fact, most resolutions will be broken before February 1. Easy to do considering that the top three most popular resolutions are all behavior modifications: lose weight, quit smoking and exercise. Well, Herbal Remedies has the answers to achieving these goals without the harmful side effects of chemical abuse. The exercise is all on you, although we can help you get the energy you need to sustain your workout naturally. The Stroke of Midnight won’t be a problem with Herbal Remedies! Herbal Remedies New Years Specials- Just in Time to keep you on track with your New Year Goals! Be sure to check out all of our Savings and with these kind of prices you can afford to stock up! QUESTIONS AND ANSWERS Q: Subject: Hello Good Afternoon, I am a person who is extremly interested in purchasing this product, however I have a couple of concerns. When reading the information on the website I just need some clarifications in regards to this part in the QandA. What benefits can I expect to see from taking F.A.S.T. supplements? Maximum rate of hair growth, sheen/lustre and enhanced general appearance of hair. Most people will observe benefits to their appearance of skin and nails, with healthier supple skin and stronger, faster growing nails. FAST supplements will not cause hair to grow or reverse the thinning process. Can you please explain to me what the highlighted part means? Thank you for your time. A: Dear Customer, This simply means it will not cause your hair to grow or stop thinning it will only increase the rate of growth of your hair by as much as 45% . If you are looking at hair LOSS products then Nisim shampoo, conditioner, and extract kit will control excessive hair loss in one week guaranteed. Thank you and All my best, Thank you for your interest in Herbal Remedies.com and the opportunity to serve you. Heather * The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products. Our Sponsors Enter coupon code "NL021909" when checking out to obtain discounts on your next purchase from http://www.HerbalRemedies.com. How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.49 automatic shipping discount for orders over $95. The more you order the more you save!!! All previous sales and previous sale items excluded , only one coupon code per order. Please note to enter coupon last after free shipping credit has adjusted.

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Melatonin May Help Eye Health By Greg Arnold, DC, CSCS, December 2, 2008, abstracted from “Therapeutic Effect of Melatonin in Experimental Uveitis” in the December 2008 issue of the American Journal of Pathology Uveitis is an inflammation inside the eye, affecting a structure called the uvea, which provides most of the blood supply to the retina. While known causes of uveitis include autoimmune diseases (lupus, rheumatoid arthritis, etc.), infection , or exposure to toxins, in many cases the cause remains unknown (1). If the inflammation that is the hallmark of uveitis is prolonged, it can cause spotty areas of scarring and result in vision loss (1). In fact, uveitis makes up 10% of blindness in persons younger than 65 years (2). Because the primary treatment goal for uveitis is to decrease inflammation, corticosteroids are the medications of choice. The initial maximum daily dosage is 1.0 to 1.5 mg per kg body weight of prednisone for two to three weeks (2). Now a new study in mice (3) has found that melatonin , known to help with heart health (4), ear health (5), cholesterol health (6), and lung health (7), may also help with eye health . In the study, research simulated uveitis in one eye of mice by injecting a sugar called LPS from the bacterium Salmonella typhimurium. The mice were then given either 5 mg per day of melatonin or placebo through the skin for 8 days. The researchers then graded the appearance of both the uveitis eye and control eye on a scale from 0 to 16 in both the melatonin mice and the control group mice. They also measured inflammation levels in the eye. As expected, inflammation increased significantly in the uveitis-induced eyes compared to placebo, with “severe inflammatory signs of uveitis” recognized within 24 hours after injection. While inflammation decreased in the control group uveitis-injected eyes 8 days later, significant eye damage was present, including “disorganization” of eye cells and even retinal detachment that persisted throughout the study period. In the melatonin-treated mice, however, there was "a significant [33%] reduction" in inflammation in the injected eyes. When looking at increases in thickness of eye structures, such as the retina that is characteristic of uveitis, control group injected eyes had retinas that were 192% thicker than eyes injected with melatonin, proving that melatonin's inhibition of inflammation helped preserve the health of the eye. For the researchers, the results of this study “support the use of melatonin as a new therapeutic strategy for the treatment of uveitis.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 “Uveitis” posted on www.nlm.nih.gov/MEDLINEPLUS/ency/article/001005.htm 2 Walling AD. Avoiding Blindness Resulting from Chronic Uveitis. AAFP 2000. Available at www.aafp.org/afp/20000715/tips/7.html 3 Sande PH. Therapeutic Effect of Melatonin in Experimental Uveitis. American Journal of Pathology. 2008;173:1702-1713 4 Cagnacci A. Prolonged Melatonin Administration Decreases Nocturnal Blood Pressure in Women. Am Jou Hypert 2006; 18(12): 1614-1618 5 Uchechukwu C. The Effects of Melatonin on Tinnitus and Sleep. Otolaryngology: Head and Neck Surgery 2006; 134(2): 210-213 6 Tamura H. Melatonin treatment in peri- and postmenopausal women elevates serum high-density lipoprotein cholesterol levels without influencing total cholesterol levels. Pineal Res 2008; 45(1):101-5. Epub 2008 Feb 19 7 Francineide L. Campos, Francisco P. da Silva-Júnior, Veralice M. S. de Bruin, and Pedro F. C. de Bruin Melatonin Improves Sleep in Asthma: A Randomized, Double-blind, Placebo-controlled Study. Am. J. Respir. Crit. Care Med. 2004; 170: 947-951

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Vitamin D Deficiency May Carry Long-Term Disease Risks By Greg Arnold, DC, CSCS, December 30, 2008, abstracted from “Does Vitamin D Make the World Go ‘Round’?“ in the December 2009 issue of Breastfeeding Medicine Vitamin D has been known to benefit bone health since it was discovered in the 1920s to cure rickets (1). But there have been remarkable discoveries of additional vitamin Dl health benefits, including heart health (2), prostate health (3), and mental health (4). Despite these abundant health benefits, current recommendations by the National Institutes of Health are still 200 IU for people up to 50 years of age, 400 IU for people 51-70 years, and 600 IU for 71 years and older (5). But vitamin D’s role in health has caused the American Academy of Pediatrics to recommended doubling the intake for children to 400 IU per day (6). It is thought that the reluctance to raise the vitamin D recommendations come from research reporting instances of vitamin D toxicity, but only after taking hundreds of thousands of IU of vitamin D for weeks to months (7, 8). Now a new study (9) has found that serious consideration must be given to increasing vitamin D recommendations, as long-term disease risks may be associated with vitamin D deficiency. Although researchers cited vitamin D’s role in cardiovascular disease (10), multiple sclerosis (11), rheumatoid arthritis (12), type 1 and 2 diabetes (12), and at least 15 types of cancers (13, 14, 15), there was still no direct evidence that vitamin D deficiency caused these diseases. However, research has shown that vitamin D helps immune system function, which has researchers suggesting that vitamin D may have “profound implications” for long-term health (16, 17). These immune system benefits have been achieved with vitamin D blood levels 54–90 ng/mL (18), which can be achieved through supplementation of 5,000 IU per day (19). For the researchers, “we have come to appreciate [vitamin D’s] significance in maintaining the health status of humans throughout the lifespan.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1. Park E. The etiology of rickets. Physiol Rev 1923;3:106–119. 2. Giovanucci E. 25-Hydroxyvitamin D and Risk of Myocardial Infarction in Men: A Prospective Study. Arch Intern Med. 2008;168(11):1174-1180 3. Bao BY. Protective role of 1, alpha-25-dihydroxyvitamin D3 against oxidative stress in nonmalignant human prostate epithelial cells. International Journal of Cancer 2008; 122(12): 2699-2706 4. Evatt ML. Prevalence of Vitamin D Insufficiency in Patients With Parkinson Disease and Alzheimer Disease.Arch Neurol. 2008;65(10):1348-1352 5. “Vitamin D” posted on the office of dietary supplements http://ods.od.nih.gov/factsheets/vitamind.asp 6. Wagner CL. Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents. Pediatrics 2008;122:1142–1152 7. DeWind L. Hypervitaminosis D with osteosclerosis. Arch Dis Child 1961;36:373–380. 8. Down P, Polak A, Regan R. A family with massive acute vitamin D intoxication. Postgrad Med J 1979;55:897–902. 9. Wagner CL. Does Vitamin D Make the World Go ‘Round’? Breastfeeding Medicine. December 2008, 3(4): 239-250 10. Forman JP, Giovannucci E, Holmes MD, et al. Plasma 25-hydroxyvitamin D levels and risk of incident hypertension.Hypertension 2007;49:1063–1069. 11. Hayes CE. Vitamin D: A natural inhibitor of multiple sclerosis.Proc Nutr Soc 2000;59:531–535. 12. Merlino LA, Curtis J, Mikuls TR, et al. Vitamin D intake is inversely associated with rheumatoid arthritis: Results from the Iowa Women’s Health Study. Arthritis Rheum 2004;50:72–77. 13. Garland C, Comstock G, Garland F, et al. Serum 25(OH)D and colon cancer: Eight-year prospective study. Lancet 1989;2:1176–1178. 14. Garland F, Garland C, Gorham E, et al. Geographic variation in breast cancer mortality in the United States: A hypothesis involving exposure to solar radiation. Prev Med 1990;19:614–622. 15. Grant WB. An estimate of premature cancer mortality in the US due to inadequate doses of solar ultraviolet-B radiation.Cancer 2002;94:1867–1875. 16. Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311:1770–1773. 17. Martineau AR, Wilkinson RJ, Wilkinson KA, et al. A single dose of vitamin D enhances immunity to mycobacteria. Am Rev Respir Crit Care Med 2007;176:208–213. 18. Haddock L, Corcino J, Vazquez MD. 25(OH)D serum levels in the normal Puerto Rican population and in subjects with tropical sprue and parathyroid disease. Puerto Rico Health Sci 1982;1:85–91. 19. Vieth R, Chan PCR, MacFarlane GD. Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level (LOAEL). Am J Clin Nutr 2001;73:288–294.

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Broccoli Compound Shown to Benefit Breast Cell Health By Greg Arnold, DC, CSCS, December 29, 2008, abstracted from “Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane” in the December 2008 issue of Carcinogensis. Cruciferous vegetables are perhaps the most nutritious class of vegetables because they all contain phytochemicals, vitamins and minerals , and fiber that are important to your health. Cruciferous vegetables include broccoli , cauliflower , Brussels sprouts , kale, cabbage , and bok choy (1). Of these vegetables, broccoli has long been known to benefit many areas of health, including prostate health (2), colon health (3), detoxification (4), immune system (5), pregnancy (6), breast cell health (7), bladder health (8), stomach health (9), heart health (10) and blood vessel health (11). Now a new study (12) has found that sulforaphane (SFN), an antioxidant in broccoli, may benefit breast health. Breast cancer is second only to lung cancer in cancer deaths of women, with an estimated 40,580 deaths in 2004 (13). It is estimated that breast cancer accounted for up to 25% of the $156.7 billion in cancer costs in the U.S. in 2001 (14). In the study, researchers exposed breast cancer cells to SFN at a concentration of 15 micromoles. They found that SFN was able reduce division of breast cancer cells by as much as 50%. Specifically, sulforaphane “significantly modified” the structure of the cell proteins during division, which is nearly identical to the way prescription drugs help treat cancer cells (15, 16). For the researchers, suflforaphane “[stops cell division of cancer cells] in a manner weaker than but similar to more powerful…anticancer drugs and strongly supports the [idea] that [stopping cell division] is important for sulforaphane’s [anti-cancer] activity.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1. “The Super-Veggies: Cruciferous Vegetables” posted on www.webmd.com/food-recipes/news/20070419/super-veggies-cruciferous-vegetables 2. Wang, L., et al., Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention. Int J Oncol, 2004. 24(1): p. 187-92 3. Gamet-Payrastre, L., et al., Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res, 2000. 60(5): p. 1426-33 4. Kim HJ. Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells. Journal of Allergy and Clinical Immunology (Elsevier). Published online ahead of print 5 March 2008, doi:10.1016/j.jaci.2008.01.016 5. Finley JW. The antioxidant responsive element (ARE) may explain the protective effects of cruciferous vegetables on cancer. Nutr Rev. 2003 Jul;61(7):250-4. Review 6. Williams DE. Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene. Carcinogenesis Advance Access published on May 16, 2006 Carcinogenesis 2006 27: 2116-2123 7. Jackson, S.J. and K.W. Singletary, Sulforaphane inhibits human mcf-7 mammary cancer cell mitotic progression and tubulin polymerization. J Nutr, 2004. 134(9): p. 2229-36 8. Munday R. Inhibition of Urinary Bladder Carcinogenesis by Broccoli Sprouts. Cancer Res 2008 68: 1593-1600. Published Online First February 29, 2008. doi: 10.1158/0008-5472.CAN-07-5009 9. “Broccoli Sprouts Relieve Gastritis in H. pylori Patients; May Help Prevent Gastric Cancer (Abstract #3442)” posted on posted on the American Association for Cancer Research Website www.aacr.org/Default.aspx?p=1275&d=553 10. Maiyoh GK. Cruciferous Indole-3-Carbinol Inhibits Apolipoprotein B Secretion in HepG2 Cells. J. Nutr. 137: 2185–2189, 2007. 11. Xue M. Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes 2008; 57(10): 2809-2817 12. Azarenko O. Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane. Carcinogenesis 2008 29(12):2360-2368; doi:10.1093/carcin/bgn241 13. "2004/2005 Fact Sheet Cancer Registries: The Foundation for Cancer Prevention and Control" posted on the CDC website http://www.cdc.gov/cancer 14. Radice D. Breast cancer management: quality-of-life and cost considerations. Pharmacoeconomics 2003;21(6):383-96 15. Kelling J, et al. Suppression of centromere dynamics by Taxol in living osteosarcoma cells. Cancer Res. (2003) 63:2794–2801 16. Okouneva T, et al. The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics. Mol. Cancer Ther. (2003) 2:427–436

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Fish Oil Component Found Helpful for Lung Health By Greg Arnold, DC, CSCS, December 29, 2008, abstracted from “Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells” printed online ahead of print in Clinical Nutrition Fish oil has been shown to benefit blood vessel health (1), digestive health (2), heart attacks bone health (3) and heart health (4). Its underlying mechanism is its ability to help maintain healthy levels of inflammation , which can cause a number of health problems. A component of fish oil called EPA has been shown to help maintain health inflammation levels by preventing a protein called arachidonic acid (AA) from stimulating the production of other inflammatory proteins (5). Now a new study (6) has found that EPA may help with lung health and asthma , which affects more than 20 million Americans (including 6.1 million children) (7). It is recognized as “a major public health problem of increasing concern in the United States,” is the third-ranking cause of hospitalization among those younger than 15 years of age, and costs $3.2 billion and accounts for 14 million lost school days each year (8). In the study, researchers obtained lung tissue samples from 20 non-smoking adults with diagnosed asthma and no history of taking omega-3 supplements. The lung cells were then exposed to and inflammatory protein called LPS and then immersed in one of 6 different treatments: Group 1: EPA only Group 2: A fish-oil solution with 45% EPA and 10% DHA (another fish oil component) Group 3: DHA only Group 4: A fish oil solution with 10% EPA and 50%) Group 5: An omega-6 fat sample Group 6: Placebo They then measured levels of inflammation throughout the samples. The researchers used either 25 or 120 micromoles of the fish oil (milligram doses were not given). The researchers found that the EPA samples had levels of 2 inflammatory proteins called LTB4 and TNF-alpha that were 72% and 60% lower than the control group, respectively. When compared to the DHA-only sample, inflammation in the EPA-only sample was 74% and 60% lower, respectively, showing EPA to be far more effective than DHA in helping control inflammation. For the researchers, the present study has shown for the first time that EPA is a more potent inhibitor than DHA of inflammatory responses in human asthmatic…cells.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1. Engler, M. M., M. B. Engler, et al. (2004). "Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study." Int J Clin Pharmacol Ther 42(12): 672-9 2. Camuesco D. Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis. J Nutr 2005 Apr;135(4):687-94 3. Rahman M. Effect of fish oil on bone mineral density in aging in C57BL/6 female rats. Nutr Biochem 2007 Jun;18(6):372-9. Epub 2006 Sep 8 4. F.C. Thien, M.P. Hallsworth, C. Soh and T.H. Lee, Effects of exogenous eicosapentaenoic acid on generation of leukotriene C4 and leukotriene C5 by calcium ionophore-activated human eosinophils in vitro, J Immunol 150 (8 Pt 1) (1993), pp. 3546–3552 5. Mozaffarian D. Dietary Fish and n-3 Fatty Acid Intake and Cardiac Electrocardiographic Parameters in Humans. Jou Am Coll Cardiol 2006; 48(3): 478-484 6. Mickleborough TD. Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells. Clin Nutr 2008. doi:10.1016/j.clnu.2008.10.012 7. Asthma” posted on the American Lung Association Website www.lungusa.org 8. CDC’s National Center for Environmental Health Website. “Asthma's Impact on Children and Adolescents” www.cdc.gov/asthma/children.htm#asthma_control

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Study Finds Hypertension Medications May Cause Diabetes by Depleting Potassium Levels By Greg Arnold, DC, CSCS, December 1, 2008, abstracted from “Changes in Serum Potassium Mediate Thiazide-Induced Diabetes” in the December 2008 issue of Hypertension High blood pressure (HBP) affects more than 65 million American adults (1) and nearly 1 billion people worldwide (2). The death rate from HBP increased by 26.8% from 1992-2002, causing nearly 50,000 American deaths in 2002 alone (1). High blood pressure is a significant risk factor for cardiovascular disease (2) and has been deemed a worldwide epidemic (3). While there are a number of natural ways help maintain healthy blood pressure, including fish oil (4), calcium (5) (12), cocoa (6), magnesium (7), soy nuts (8), fiber (9), whole grain foods (10), whey protein (11), hawthorn extract (13), and vitamin D (14), sometimes prescription medication is needed. One of the most common classes of medications prescribed as a “first-line therapy” for HBP are Thiazides, accounting for 25% of all first-line HBP medication prescriptions (15). But one of the most serious side effects of taking thiazides is becoming a diabetic . In the Systolic Hypertension in the Elderly Program (SHEP), use of the thiazides was associated with a 50% higher risk of diabetes, compared with placebo (16). And it is this increased risk of diabetes that limits doctors from prescribing thiazides more often to help manage HBP, despite recommendations from the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (17). Now a new study (18) has found that thiazides may be increasing the risk for diabetes by depleting potassium levels in your body. In the study, researchers analyzed data from 3790 non-diabetic participants in the SHEP. When all factors were considered, use of thiazides increased diabetes risk by 107%, but when looking at potassium levels, the risk was cut to 54%. Furthermore, each 0.5-milliequivalents per liter decrease in potassium levels was independently associated with a 45% higher risk for diabetes For the researchers, “thiazide-induced diabetes…appears to be mediated by changes in serum potassium” and that “potassium supplementation might prevent thiazide-induced diabetes.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1. “High Blood Pressure Statistics” posted on the American Heart Association website http://www.americanheart.org/presenter.jhtml?identifier=4621 2. David Conen D. Blood pressure progression: prospective cohort study with high normal blood pressure or blood Risk of cardiovascular events among women. BMJ published online 19 Aug 2007; doi:10.1136/bmj.39269.672188.AE 3. Casas JP. Homocysteine and stroke: evidence on a causal link from mendelian randomization. Lancet 2005; 365(9455): 224-232 4. Rousseau D. Dietary n-3 PUFAs affect the blood pressure rise and cardiac impairments in a hyperinsulinemia rat model in vivo. Am J Physiol Heart Circ Physiol 2003 Sep;285(3):H1294-302 5. Arends LR. Blood pressure response to calcium supplementation: a meta-analysis of randomized controlled trials. J Hum Hypertens 20: 571-580 6. Taubert D. Effect of Cocoa and Tea Intake on Blood Pressure. Arch Intern Med. 2007;167:626-634 7. Altura BM. Magnesium and cardiovascular biology: an important link between cardiovascular risk factors and atherogenesis. Cell Molecule and Biology Research 1995; 41(5): 347-359 8. Welty FK. Effect of Soy Nuts on Blood Pressure and Lipid Levels in Hypertensive, Prehypertensive, and Normotensive Postmenopausal Women. Arch Int Med 2007; 167(10): 1060-1067 9. Whelton, SP. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trials. J Hypertens. 2005 Mar;23(3):475-81 10. Behall KM. Whole-Grain Diets Reduce Blood Pressure in Mildly Hypercholesterolemic Men and Women. Jou Am Diet Assoc 2006; 106 (9): 1445-1449 11. Pins JJ. Effects of Whey Peptides on Cardiovascular Disease Risk Factors. J Clin Hypertens (2006) 8;11:775-782 12. Arends LR. Blood pressure response to calcium supplementation: a meta-analysis of randomized controlled trials. J Hum Hypertens 20: 571-580 13. Walker AF. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen Pr 2006;56(527):437-43 14. Forman JP. Plasma 25-Hydroxyvitamin D Levels and Risk of Incident Hypertension Among Young Women. Hypertension. 2008;52:828-832; published online before print October 6 2008, doi:10.1161/HYPERTENSIONAHA.108.117630 15. “Reducing Antihypertensive Drug Costs by Regulatory Intervention May Be Effective in the Long Term” posted on Medscape.com 16. Kostis JB, Wilson AC, Freudenberger RS, Cosgrove NM, Pressel SL, Davis BR, Group SCR. Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes. Am J Cardiol. 2005; 95: 29–35 17. Verdecchia P, Angeli F, Reboldi G. New-onset diabetes, antihypertensive treatment, and outcome. Hypertension. 2007; 50: 459–460 18. Shafi T. Changes in Serum Potassium Mediate Thiazide-Induced Diabetes. Hypertension 2008 ;52:1022-1029 Do you have a question for us? If so please send in your questions to newsletter@herbalremedies.com We will answer all email ASAP!

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For assistance or to purchase products by phone call toll free in the USA 1-866-467- 6444 or World Wide 1-307-577-6444 or e-mail your questions to newsletter@herbalremedies.com. We will answer e-mails in the newsletter as space allows. Our Sponsors HerbalRemedies.com Get the finest all natural health products, get the best service, and low cost worldwide delivery. Enter coupon code "NL021909" when checking out to obtain discounts on your next purchase from www.HerbalRemedies.com How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.49 automatic shipping discount for orders over $95. The more you order the more you save!!! Only one coupon per order! Please note to enter coupon last after free shipping credit has adjusted.