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Home > Supplement Dictionary - All Herbal Supplements, Dietary Supplements & Information > L-tryptophan Supplements and Products > 

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L-Tryptophan General Information
L-Tryptophan Uses & Scientific Evidence For
L-Tryptophan Dosage Information
L-Tryptophan Safety & Interaction Information

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L-Tryptophan General Information
Tryptophan, an essential amino acid, is the precursor to Serotonin, which is a necessary neurotransmitter responsible for transmitting nerve impulses in the brain, and inducing sleep and tranquility. Serotonin deficiencies, which are related to Tryptophan deficiencies, are well documented in cases of depression and insomnia. If needed, L-tryptophan converts to niacin in the body, which supports circulation, a healthy nervous system, the metabolism of food, and the production of hydrochloric acid for the digestive system. L-Tryptophan also supports immune functions because it is the body's precursor to the kynurenines that regulate immunity.

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L-Tryptophan Uses & Scientific Evidence For
Tryptophan is very important for biochemical balance of the brain, and is very helpful for those with sleep deprivation, anxiety and mood enhancement due to low Serotonin levels. It also helps to biochemical balance the brain in those whose Serotonin levels are low because of chemical addictions. It has also been effective in appetite control, increasing pain tolerance and assisting those with jet lag. Because Tryptophan is the least abundant amino acid in our diet, it should be no surprise that Tryptophan supplements have been widely used to correct deficiencies for more than a quarter of a century by doctors in the United States and Europe. Psychiatrists, medical doctors, and nutritionists, alike, have long recognized the importance of pure Tryptophan for maintaining good health, relieving poor mood and irritability, reducing the craving for carbohydrates, and normalizing sleep.

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L-Tryptophan Dosage Information
When L-Tryptophan is indicated, a common dosage is one 500 mg capsule for every 50 lbs of body weight, one hour before bedtime, or as directed by a healthcare professional. Dosage may be reduced as sleep improves. When indicated, allow sixty days for optimal results. With any new supplement, it is best to start with a low dose and work up to the desired dose gradually. Also, because several other amino acids may compete with L-Tryptophan for absorption, it is best given with a beverage or a snack containing minimal protein. Carbohydrates help to facilitate the passage through the blood-brain barrier. It is best to read product label directions for guidelines on the dosage recommended for your specific condition. Although some symptoms of an L-Tryptophan deficiency may disappear quickly, others may take time to show improvement. Essential amino acids are involved in a myriad of structural proteins and enzymes, as well as neurotransmitters, and so replacement may take time.
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L-Tryptophan Safety & Interaction Information
L-Tryptophan is considered safe as a dietary supplement. L-Tryptophan was a very popular sleeping aid in the U.S. until recently, and was also used for premenstrual syndrome and depression. The FDA (Food and Drug Administration) placed an Import Alert on this products in 1990 when one Japanese manufacturer sent several contaminated batches to the US. Our supplier has been thoroughly and independently tested and provides one of the purest L-Tryptophan products in the world today. Consult your physician if you are taking any other medications. Not recommended for use with MAOIs (monoamine oxidase inhibitors). Safety in young children, pregnant or nursing women, or those with severe liver or kidney disease is not known. Other drugs may interact with L-tryptophan. Tell your doctor or care practitioner about all the prescription and over-the-counter medications you use. Before taking L-tryptophan, tell your doctor or other care practitioner if you have:liver disease,kidney disease,eosinophilia, or a muscle disorder (such as fibromyalgia). If you have any of the conditions listed above, you may not be able to use L-tryptophan, or you may need a dosage adjustment or special tests during treatment.

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