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Herbal Remedies Natural Health Newsletter, May 2007, Issue 271

Herbal Remedies May 2007 Natural Health Newsletter Issue 271 Sponsored by www.HerbalRemedies.com Toll Free for orders 1-866-467-6444 Issue Editor - Heather Bowman

Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books Study Finds How Curcumin Helps Maintain Cell Health - Click here for full story. Study Finds Low-Dose Folic Acid Improves Heart Health - Click here for full story. Study Re-Confirms Cocoa's Benefits for Blood Pressure - Click here for full story. Soy Found Beneficial for Women's Bones - Click here for full story. Study Finds Antioxidant Supplementation May Help Maintain Eye Health - Click here for full story. Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies Be sure to check out our Overstocked savings! OVERSTOCKED Do you want to control your seasonal allergies without the side effects? Let us help with our all Natural Allergy relief products and Hayfever remedies! Be sure to check out our best seller Allergiemittel and one of Herbal Remedies employees personal favorites! Herbal Remedies has three new vendors be sure to check them out: Allergy Research Group , New Age Imports, Inc., and Earth Solutions Products Spotlight – Need to find something that really shows Daddy how much you care? With all the honey-do’s Daddy doesn’t get much time to take care of himself and that is where children everywhere need to be their little nutritional advisors. Herbal Remedies has just the right products with Daddy in mind, so just relax and let us point you in the right direction. Let this Father’s Day be therapeutic for Dad...HAPPY FATHER'S DAY! Current Event News: Afraid that you may be the next victim of a heart attack or a stroke? Every year, more than a million Americans are sadly enough struck down by a heart attack or stroke . Those lucky enough to survive often face invasive procedures like angioplasty, followed by a lifetime of curtailed physical activity and costly heart medications that have adverse side effects. Although cardiovascular disease remains the nation’s number-one killer, American medicine prioritizes heart disease treatment rather than prevention. Sadly, it has become far more profitable to treat heart disease than to prevent it. Fortunately, natural strategies that can help avert life-threatening heart attacks and strokes are readily available today. One of the most promising heart-protective agents to emerge in recent years is pomegranate . Packed with unique antioxidants that guard the body’s endothelial cells against free-radical assault, pomegranate has been shown to prevent—and even reverse—cardiovascular disease. Research also shows that pomegranate can stop the progression of deadly prostate cancer. And scientists are now exploring pomegranate’s potential in averting ailments ranging from diabetes to Alzheimer’s disease , as well as its role in supporting skin, joint, dental, and liver health. To make your online shopping even more convenient for you we have a vast selection of products priced with you in mind in our RED HOT SALE ITEMS QUESTIONS AND ANSWERS Q: Subject: Hello I have read good things about products from Vital Earth helping with or even curing hyperthyroid. I would like to use them but feel concerned tha they may make my vitiligo worse. I would also like to use the bakuchi powder to stimulate the production of melanin in my skin. Do you know what oil you would mix it with to make something I can apply to the skin? Many thanks A: Dear Customer, Here are great informational links on hyperthyroid and vitiligo and list of products. I would have to know which Vital Earth product you were referring to in order to provide more information as we have an extensive list. The bakuchi powder can be taken orally to aid the skin but if you were wanting to apply it to the skin primrose oil is nice as it is one of the supplements listed in beneficial dietary supplements for skin pigmentation associated with vitiligo. All my best, Thank you for your interest in Herbal Remedies.com and the opportunity to serve you. Heather * The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products. Our Sponsors Enter coupon code "NL052907" when checking out to obtain discounts on your next purchase from http://www.HerbalRemedies.com. How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.99 automatic shipping discount for orders over $95. The more you order the more you save!!! All previous sales and previous sale items excluded , only one coupon code per order

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Study Finds How Curcumin Helps Maintain Cell Health By Greg Arnold, DC, CSCS, April 16, 2007, abstracted from “Curcumin, a Dietary Component, Has Anticancer, Chemosensitization, and Radiosensitization Effects by Down-regulating the MDM2 Oncogene through the PI3K/mTOR/ETS2 Pathway” in the March 1, 2007 issue of Cancer Research The roots of curcuma longa, a ginger-like plant that grows in tropical regions, have a bright yellow substance (turmeric) that contains curcumin and other curcuminoids. Although it has been used for centuries in Ayurvedic and Chinese medicine, only within the past few years has western medicine taken note of curcumin’s health-promoting properties.(1) In addition to showing potential to help keep cholesterol in normal range,(2) curcumin helps protect cells against the damage of smoking and drinking(3) and even helps promote brain,(4) colon,(5) digestive(6) and breast cell health.(7) Now a new study(8) may have identified the mechanism by which curcumin exerts all of these health effects. In the study, researchers found that curcumin decreases activity of MDM2 in both normal and cancer cells. MDM2, a protein that accelerates cell division, is “an important mediator of growth and survival” of cells(9) and whose over-expression is associated with a poor cancer outcome.(10) The other breakthrough regarding the down-regulation of MDM2’s activity is that it occurred independent of the p53 tumor suppression protein and elucidated a possible new and unique target in the progression of cancer and that For the researchers, “down-regulation of the MDM2 [cancer] gene by curcumin is a [new] mechanism of action that may be essential for [curcumin’s] chemopreventive and chemotherapeutic effects.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 Mitchell T. A Report on Curcumin’s Anti-Cancer Effects. Life Extension Magazine, July 2001 2 Peschel D. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. Jou Nutr Biochem. In Press, Corrected Proof, Available online 18 May 2006 3 Vanisree AJ. Curcumin Combats Against Cigarette Smoke and Ethanol-Induced Lipid Alterationsin Rat Lung and Liver. Mol Cell Biochem 2006, posted online May 12, 2006 4 Common spice may slow Alzheimer's. Health News. 2005 Apr;11(4):2 5 Sanchez P. Combination Treatment with Curcumin and Quercetin of Adenomas in Familial Adenomatous Polyposis. Clin Gastroenterol Hepatol 2006 Aug; 4(8):1035-1038 6 Tunstall RG. Cyclooxygenase-2 expression and oxidative DNA adducts in murine intestinal adenomas: Modification by dietary curcumin and implications for clinical trials. Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4 7 Aggarwal BB. Curcumin Suppresses the Paclitaxel-Induced Nuclear Factor- B Pathway in Breast Cancer Cells and Inhibits Lung Metastasis of Human Breast Cancer in Nude Mice. Clin Cancer Res 2005 11: 7490-7498 8 Li M. Curcumin, a Dietary Component, Has Anticancer, Chemosensitization, and Radiosensitization Effects by Down-regulating the MDM2 Oncogene through the PI3K/mTOR/ETS2 Pathway. Cancer Research 67, 1988-1996, March 1, 2007. doi: 10.1158/0008-5472.CAN-06-3066 9 Levay-Cohen Y. Mdm2 in growth signaling and cancer. Growth Factors. 2005 Sep;23(3):183-92. 10 Poyurovsky MV, Prives C. Unleashing the power of p53: lessons from mice and men. Genes Dev 2006;20:125–31 Disclaimer: Claims made by NOW Foods for Curcumin as a dietary supplement are regulated by the FDA, and any claims made in the above article are not made by NOW Foods.

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Study Finds Low-Dose Folic Acid Improves Heart Health By Greg Arnold, DC, CSCS, April 26, 2007, abstracted from “Global Improvement of Vascular Function and Redox State with Low-Dose Folic Acid. Implications for Folate Therapy in Patients with Coronary Artery Disease” printed online in Circulation Journal Folic acid is a B-vitamin whose fortification in food is best known for helping decrease neural tube deficits by as much as 23%.(1) Its health benefits also extend to mental ,(2) digestive (3) and immune system (4) health. But folic acid’s most impressive health benefit may lie in its ability to help lower homocysteine levels(5) and improve heart and blood vessel health. A new study(6) has found that folic acid’s lowering of homocysteine levels improves blood vessel health. In the study, 56 patients with Coronary Artery Disease (CAD) received either low-dose (400 micrograms per day) or high-dose (5 milligrams per day) folic acid or placebo for seven weeks before coronary artery bypass grafting. Blood vessel function was measured using magnetic resonance imaging before and after treatment. At the end of seven weeks, the researchers found that low-dose folic acid increased blood vessel dilation responses by improving its sensitivity to nitric oxide, a strong blood vessel dilator, as well as reducing oxidative stress to the blood vessels. These improvements were not increased, however, in the high-dose compared with low-dose treatment. For the researchers, “low-dose folic acid treatment…improves vascular function through effects on…nitric oxide synthase and…oxidative stress.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting www.CompleteChiropracticHealthcare.com Reference: 1 “Spina Bifida and Anencephaly Before and After Folic Acid Mandate --- United States, 1995--1996 and 1999—2000” from MMWR Weekly 2004; 53(17): 362-365 2 “The First Ever Dementia Conference Opens In Washington, DC” posted on the Alzheimer’s Association Website 3 Danese S. Homocysteine triggers mucosal microvascular activation in inflammatory bowel disease. Am J Gastroenterol. 2005 Apr;100(4):886-95 4 C.J. Field, I.R. Johnson and P.D. Schley, Nutrients and their role in host resistance to infection, J Leukoc Biol 71 (2002), pp. 16–32 5 Davey-Smith G. Meta-analysis of the MTHFR C to T polymorphism and coronary heart disease; does the totality of evidence support a causal role for homocysteine and the preventive potential of folate? BMJ 2005;331:1053-6

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Study Re-Confirms Cocoa's Benefits for Blood Pressure By Greg Arnold, DC, CSCS, April 13, 2007, abstracted from “Effect of Cocoa and Tea Intake on Blood Pressure” in the April 9, 2007 issue of the Archives of Internal Medicine High blood pressure is estimated to affect 65 million Americans aged 20 years and older and the death rate from this condition increased by 26.8% from 1992-2002. In 2002 alone, high blood pressure killed nearly 50,000 Americans(1) and is now a worldwide epidemic.(2) Although fiber plays a key role(3) in helping keep your blood pressure in normal range, the high polyphenol content of fruits and vegetables (4) makes them the #1 nutritional recommendation to help you control your blood pressure.(5) But while tea and cocoa are also high in polyphenols and make up the majority of the polyphenol intake in Western Countries,(6) they are not on the list of recommended foods. Now a new study(7) has built upon previous research showing cocoa’s ability to help preserve blood vessel health(8) and reconfirms its potential to be a recommended food for healthy blood pressure. In the study, researchers examined five randomized controlled trials of at least seven days of cocoa, black or green tea’s effect on high blood pressure. They found that with polyphenol intake ranging from 213-500 mg per day, patients in the cocoa groups had an average drop of 4.7 mm Hg in diastolic blood pressure (the top number) and a 2.8 mm Hg drop in systolic blood pressure. The explanation given by the researchers for cocoa’s effect is thought to be its ability help relax blood vessels.(9) They found no significant effect of tea on blood pressure. For the researchers, “consumption of foods rich in cocoa may reduce blood pressure, while tea intake appears to have no effect.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 “High Blood Pressure Statistics” posted on the American Heart Association website http://www.americanheart.org/presenter.jhtml?identifier=4621 2 Casas JP. Homocysteine and stroke: evidence on a causal link from mendelian randomization. Lancet 2005; 365(9455): 224-232 3 Whelton, SP. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trials. J Hypertens. 2005 Mar;23(3):475-81 4 He FJ, Nowson CA, MacGregor GA. Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. Lancet. 2006;367:320-326 5 Chobanian AV, Bakris GL, Black HR, et al, National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289:2560-2572 6 Weisburger JH. Lifestyle, health and disease prevention: the underlying mechanisms. Eur J Cancer Prev. 2002;11(suppl 2):S1-S7 7 Taubert D. Effect of Cocoa and Tea Intake on Blood Pressure. Arch Intern Med. 2007;167:626-634 8 Fisher N. Aging and vascular responses to flavanol-rich cocoa. J Hypertension 2006; 24(8): 1575-1580 9 Karim M, McCormick K, Kappagoda CT. Effects of cocoa extracts on endothelium-dependent relaxation. J Nutr. 2000;130:2105S-2108S

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Soy Found Beneficial for Women's Bones By Greg Arnold, DC, CSCS, December 5, 2006, abstracted from “Soy protein and bone mineral density in older men and women: A randomized trial” in the November 2006 issue of Maturitas Osteoporosis is a condition most commonly associated with women; it is estimated that 8 million women have osteoporosis and is a “major public threat” for 34 million more Americans.(1) What is not well known is that nearly 2 million American men over age 50 have osteoporosis.(2) These men have a 13% lifetime risk for fracture and also have a risk of death from fracture that is higher than that seen in women.(3) And while the primary sex hormone in men is testosterone, estrogen plays just as much a role in helping maintain bone health in men as women. Its decline with age explains the presence of osteoporosis in elderly men.(4) But while soy protein has been found to help bone health in women,(5) a new study(6) has found that this benefit may not extend to men. In the study, 145 patients aged 50-80 years (22 women, 123 men) were given a soy beverage containing 83 mg isoflavones each day for 1 year. Researchers then measured bone mineral density in the hip and low back at the beginning of the study and at 12 months. They found that spine BMD was “significantly greater” in women than men in the soy group versus the control group. Changes in BMD in women in the soy group were more than triple the changes seen in the control group. While finding “no significant treatment effect on spine or hip BMD among men at either 6 or 12 months”, researchers found that “soy protein containing isoflavones showed a modest benefit in preserving spine, but not hip BMD in older women.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his web site www.CompleteChiropracticHealthcare.com Reference: 1 “Fast Facts on Osteoporosis” posted on the National Osteoporosis Foundation website 2 A.C. Looker, E.S. Orwoll and C.C. Johnston Jr. et al., Prevalence of low femoral bone density in older U S. adults from NHANES III, J Bone Miner Res 12 (1997), pp. 1761–1768 3 S. Amin, Male osteoporosis: epidemiology and pathophysiology, Curr Osteoporos Rep 1 (2003), pp. 71–77 4 C. Carani, Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho)physiology, Eur J Endocrinol 154 (2006), pp. 175–185 5 Zhang, X., X. O. Shu, et al. (2005). "Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women." Arch Intern Med 165(16): 1890-5 6 Newton KM. Soy protein and bone mineral density in older men and women: A randomized trial. Maturitas 2006; 55(3): 270-277

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Study Finds Antioxidant Supplementation May Help Maintain Eye Health By Greg Arnold, DC, CSCS, January 16, 2007, abstracted from The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract” in the February 2002 issue of Ophthalmic Epidemiology Defined as “a clouding of the lens in the eye that affects vision”, cataracts are one of the leading causes of irreversible blindness, along with age-related macular degeneration . By age 80, more than half of all Americans either have a cataract or have had cataract surgery.(1) Supplementing with vitamin E (2) and superoxide dismutase (3) and following a diet low on the glycemic index(4) may help maintain eye health . Now a new study(5) has found that including beta-carotene and vitamin C may also help maintain eye health. In the study, nearly 300 patients from the U.S. and U.K. were given either an antioxidant supplement that provided a daily dose of 18 mg of beta-carotene, 750 mg of vitamin C and 600 mg of vitamin E or placebo. The patients were followed up for two to four years (231 were followed for two years; 158 for three years and 36 (12%) for four years). Cataract severity, in the form of increasing opacity (“cloudiness”) of the lens was the main outcome measure of the study and was measured using serial digital retroillumination imagery of the lens. While there were no statistically significant differences between patients in regards to lens opacity at the beginning of the study, they found that the longer the study lasted, the greater the differences between the supplement and placebo groups. With “a small positive treatment effect” after two years of treatment, this increased after three years to “a positive effect” and was apparent in both the U.S. and the U.K. groups. For the U.S. group, however, the positive effect was even greater after three years and was thought to be related to the base diet of those in the U.S. versus the U.K. For the researchers, “Daily use of the afore-mentioned micronutrients for three years produced a small deceleration in progression of ARC.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website. Reference: 1 National Eye Institute Website 2 Jacques PF. Long-term Nutrient Intake and 5-Year Change in Nuclear Lens Opacities. Arch Ophthalmol. 2005;123:517-526 3 Reddy VN. SOD2 Protects against Oxidation-Induced Apoptosis in Mouse Retinal Pigment Epithelium: Implications for Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2005 46: 3426-3434 4 Chiu CJ. Dietary carbohydrate intake and glycemic index in relation to cortical and nuclear lens opacities in the Age-Related Eye Disease Study. Am. J. Clinical Nutrition, May 2006; 83: 1177 – 1184 5 Chylack, L.T., Jr., et al., The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract. Ophthalmic Epidemiol, 2002. 9(1): p. 49-80 Do you have a question for us? If so please send in your questions to herbalnews@qwest.net We will answer all email ASAP!

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For assistance or to purchase products by phone call toll free in the USA 1-866-467- 6444 or World Wide 1-307-577-6444 or e-mail your questions to herbalnews@qwest.net. We will answer e-mails in the newsletter as space allows. Our Sponsors HerbalRemedies.com Get the finest all natural health products, get the best service, and low cost worldwide delivery. Enter coupon code "NL052907" when checking out to obtain discounts on your next purchase from www.HerbalRemedies.comHow would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.99 automatic shipping discount for orders over $95. The more you order the more you save!!!