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Home > Herbal Remedies Natural Health Newsletter, October 2009, Issue 290 > Herbal Remedies Newsletter Archives > 

Herbal Remedies Natural Health Newsletter, July 2008, Issue 282


Herbal Remedies Natural Health Newsletter, July 2008, Issue 282


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Herbal Remedies July 2008
Natural Health Newsletter Issue 282
Sponsored by www.HerbalRemedies.com
Toll Free for orders 1-866-467-6444

Issue Editor - Heather Bowman
Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books
  • Vitamin E Linked to Mental Health - Click here for full story.

  • New Study Hints at Heart Health Properties of Milk Thistle - Click here for full story.

  • Vitamin D Found to Help Predict Overall Cell Health - Click here for full story.

  • Lutein and Omega-3 Both Iportant for Eye Health in Women - Click here for full story.

  • Study Uncovers How Niacin Helps Maintain Healthy Cholesterol Levels - Click here for full story.

    Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies

    Be sure to check out our Overstocked clearance items! OVERSTOCKED

    Give your skin a natural glow with Burt's Bees Products. We are your #1 Headquarters for your complete line of Burt’s Bees Products for that all around natural glow!!

    Herbal Remedies has four new vendors be sure to check them out: Herbal Remedies USA Products , Dr Bronner’s Castile Soaps , Tints of Nature/ Naked Earth Permanent Organic Hair Color Products, and Burt's Bees Men's Products

    Products Spotlight – Are the summer activities leaving you in aching pain? Rhus toxicodendron (Rhus tox.) is a remedy frequently indicated for conditions that are accompanied by fever, swollen glands, inflammation of mucous membranes and/or muscles, skin conditions, and restlessness. Homeopaths prescribe Rhus tox. for a number of complaints including poison ivy, chicken pox, back pain, colds, herpes, hives, flu, mumps, measles, sore throat, nerve pain, muscle strains and sprains, dermatitis, arthritis, bursitis, carpal tunnel, rheumatism, and fevers. Ailments arise from overexertion, a change in weather, cold/damp weather, or from getting wet or chilled. Rhus tox. is one of the best remedies indicated in chronic or acute rheumatic or arthritic conditions.

    Current Event News: Anxiety interfering with your day-to-day life? More than 65 million Americans suffer annually from the worry, panic, stress, exaggerated concern and chronic insomnia characteristic of anxiety. For many, these feelings are triggered by high-pressure jobs, relationships, financial problems, loneliness, crowds, traffic jams, travel, high places, closed in places and a myriad of other motivations.
    There is no way to prevent the development of anxiety and panic disorders, but there are methods to reduce the frequency of attacks. These tools include avoiding alcohol and caffeine; learning effective coping techniques; reducing stress; getting regular exercise; eating a healthy diet, taking dietary supplements and establishing a good, trusting relationship with a medical professional who specializes in anxiety problems. Dietary L-lysine deficiency increases stress-induced anxiety. L-lysineL-lysine supplementation lessens plasma cortisol in response to stress and reduces chronic anxiety. Calcium and Magnesium Complex offers a natural mild tranquilizing effect and relieves anxiety, nervousness and tension. Catnip, chamomile , kava kava , Hops , Motherwort and Passionflower promote relaxation and help to prevent panic attacks. These are just to name a few but an all natural approach is better than one having any dependencies to chemical prescription drugs and better on the body.

    Blistering Hot Summer Savings with our Coupon Savings and with these kind of prices you can afford to stock up!

    QUESTIONS AND ANSWERS

    Q:
    Subject: Hello
    Hi Does Nisim hair care products actually regrow hair or does it only stop hair loss and thicken hair?

    Many thanks

    A:
    Dear Customer,
    Nisim shampoo and stimulating extract were clinically proven to regrow hair on 85.7% of those tested. Nisim Shampoo by itself will control excessive hair loss in one week guaranteed. The active ingredients in Nisim's products are natural organic herbal extracts. The entire line of Nisim hair care products are safe for permed, colored or chemically treated hair.
    All my best,

    Thank you for your interest in Herbal Remedies.com and the opportunity to serve you. Heather
    * The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products.

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Vitamin E Linked to Mental Health

By Greg Arnold, DC, CSCS, April 21, 2008, abstracted from “Vitamin E Use Is Associated with Improved Survival in an AD Cohort” at the American Academy of Neurology 60th Anniversary Annual Meeting April 15, 2008

The incidence of Alzheimer Disease (AD) has doubled since 1980. It currently affects just under 5 million Americans and is expected to affect 16 million by 2050(1). It currently costs our healthcare system over $100 billion each year(2). Fortunately, there are some simple ways to help maintain mental health , including eating apples(3), drinking green tea (4) and taking fish oil (5). Now a new study(6) has found that vitamin E may help with mental health and AD.

In the study, 847 patients diagnosed with AD (average age 73.5 years, 67% of whom were female) were given 2000 IU of vitamin E per day and followed for just under 5 years. While two-thirds of the patients consumed the vitamin E with an AD drug called a cholinesterase inhibitor, less than 10% of the group took vitamin E alone and 15% consumed no vitamin E.

The researchers found that whether or not they were on the AD drug, vitamin E supplementation was associated with a 26% reduction in death in AD patients compared to those who didn't take vitamin E. And although the 2000 IU of vitamin E per day is significantly higher than the 22.5 IU per day in adults and 28.5 IU per day in lactating women currently recommended by the National Institute of Health(7), the researchers concluded that because “people who took [the AD drug] without vitamin E did not have a survival benefit” that ”more research needs to be done to determine why this may be the case."

Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com

Reference:

1 Hebert, LE; Scherr, PA; Bienias, JL; Bennett, DA; Evans, DA. “Alzheimer Disease in the U.S. Population: Prevalence Estimates Using the 2000 Census.” Archives of Neurology August 2003; 60 (8): 1119 – 1122

2 Ernst, RL; Hay, JW. “The U.S. Economic and Social Costs of Alzheimer’s Disease Revisited.” American Journal of Public Health 1994; 84(8): 1261 – 1264

3 Lee, C. Y. (2004). "Protective Effects of Quercetin and Vitamin C against Oxidative Stress-Induced Neurodegeneration." Journal of Agricultural and Food Chemistry 52: 7514-7517

4 Tan J. Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice J. Neurosci. 2005 25: 8807-8814

5 Wurtman RJ. Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally. In Press, Corrected Proof, Available online 21 April 2006 in Brain Research

6 American Academy of Neurology 60th Anniversary Annual Meeting 15 April 2008, Poster Sessions III: Aging and Dementia: Clinical II [P03.076] Vitamin E Use Is Associated with Improved Survival in an AD Cohort Authors: V. Pavlik, R. Doody, S. Rountree, E. Darby

7 “Vitamin E” posted on http://ods.od.nih.gov/factsheets/vitamine.asp#h3

Back to Top

New Study Hints at Heart Health Properties of Milk Thistle

By Greg Arnold, DC, CSCS, June 13, 2008, abstracted from “Milk Thistle Extracts Inhibit the Oxidation of Low-Density Lipoprotein (LDL) and Subsequent Scavenger Receptor-Dependent Monocyte Adhesion” in the 2008 issue of the Journal of Agricultural and Food Chemistry

Milk thistle is a plant that has been used since the times of ancient Greece to help treat liver and gallbladder diseases and help protect the liver against toxins. Recent uses have extended to overall cell health and as a supportive treatment for liver damage(1). The National Cancer Institute cites “very few side effects” in patients taking milk thistle. It primary component, silymarin , is “an antioxidant that protects against cell damage”(2) and has been found to help breast cell (3) and lung cell(4) health in mice.

Now a new study(5) has found that milk thistle may now benefit heart health and atherosclerosis , by helping protect cholesterol against oxidative damage. Atherosclerosis is a primary cause of heart disease , which caused 451,326 deaths in 2004 and is the single leading cause of death in America today(6). In the study, research found that milk thistle extract given to mice in 18, 36, 72, and 144 mg dosages led to “a high degree of protection” of LDL cholesterol, decreasing oxidative damage by 18%, 73%, 82%, and 86%, respectively, compared to placebo.

The researchers also measured the level of thiobarbituric reactive substances (TBARS), known to be present in high amounts in people with chronic diseases such as Alzheimer Disease (7). They found that the milk thistle extracts decreased TBARS levels by 37%, 65%, 61%, and 74%, respectively.

For the researchers, “[the] phytochemicals present in milk thistle fruit inhibited the [damage of LDL cholesterol]” and that “it is possible that the extract prepared from the fruits of an easily accessible plant could be useful to prevent the progression of atherosclerotic events.” In addition to milk thistle, other ways to help protect your cholesterol include consuming almonds(8) and you can help manage TBARS levels by taking a multivitamin supplement(9).

Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com

Reference:

1 Rainone F. Milk Thistle. Am Fam Physician 2005;72:1285

2 “Milk Thistle” posted on www.cancer.gov/cancertopics/pdq/cam/milkthistle

3 Verschoyle RD. Consumption of silibinin, a flavonolignan from milk thistle, and mammary cancer development in the C3(1) SV40 T,t antigen transgenic multiple mammary adenocarcinoma (TAg) mouse. Cancer Chemotherapy and Pharmacology 2008; 62(2): 369-372

4 Singh RP. Effect of Silibinin on the Growth and Progression of Primary Lung Tumors in Mice. J Natl Cancer Inst 2006; 98: 846-855

5 Wallace S. Milk Thistle Extracts Inhibit the Oxidation of Low-Density Lipoprotein (LDL) and Subsequent Scavenger Receptor-Dependent Monocyte Adhesion. Jou Agr Food Chem 2008; 56(11): 3966 – 3972.

6 “Cardiovascular Disease Statistics” posted on www.americanheart.org/presenter.jhtml?identifier=4478

7 Lovell MA. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 1995 Aug;45(8):1594-601

8 Chen CY. Flavonoids from Almond Skins Are Bioavailable and Act Synergistically with Vitamins C and E to Enhance Hamster and Human LDL Resistance to Oxidation. J. Nutr. 2005 135: 1366-1373

9 Guillaume Machefer. Multivitamin-Mineral Supplementation Prevents Lipid Peroxidation during "The Marathon des Sables". J. Am. Coll. Nutr. 2007 26: 111-120

Back to Top

Vitamin D Found to Help Predict Overall Cell Health

By Greg Arnold, DC, CSCS, May 28, 2008, abstracted from “Low Serum Levels of 25-Hydroxyvitamin D Predict Fatal Cancer in Patients Referred to Coronary Angiography” in the May 2008 issue of the Cancer Epidemiology Biomarkers and Prevention

As a whole, cancer is the #1 killer of Americans, passing heart disease in 2005(1). According to the National Cancer Institute, nearly 1.5 million men and women (52% men 48% women) will be diagnosed with cancer and result in an estimated 565,650 deaths in 2008(2). The American Cancer Society estimates that cancer costs our healthcare system $218 billion each year(3).

There are a number of alternative solutions to help keep our cells healthy, including green tea for prostate health(4), tea for ovarian cell health(5), lignans (6) and soy isoflavones (7) for breast cell health, and fiber for colon health(8). Now a new study(9) has found that vitamin D , known to help bone health(10), immune system health (11), blood sugar health(12), and overall health(13), may also help overall cell health regarding cancer.

In the study, researchers analyzed the blood samples of nearly 3,300 patients from The Ludwigshafen Risk and Cardiovascular Health (LURIC) study(14). They found that higher [blood levels of vitamin D] were associated with “significantly reduced risk” for fatal cancer. Specifically, after adjusting for age, sex, body mass index, smoke habits, vitamin A blood levels, exercise habits, beer and wine consumption and diabetes mellitus, those with the highest blood levels of vitamin D (more than 57.5 nanomoles per Liter) had a 55% reduced risk of all forms of cancer compared to those with the lowest blood levels of vitamin D (less than 25.5 nanomoles per Liter).

For the researchers, “our data suggest that low [blood levels of vitamin D] are associated with increased risk of fatal cancer…and that the maintenance of a sufficient vitamin D status might therefore be a promising approach for the prevention and/or treatment of cancer.”

Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com

Reference:

1 “Cancer passes heart disease as top killer” posted on www.nytimes.com/2005/01/20/health/20cancer.html

2 “Incidence and Mortality” posted on http://seer.cancer.gov/statfacts/html/all.html

3 “Costs of Cancer” posted on www.cancer.org/docroot/MIT/content/MIT_3_2X_Costs_of_Cancer.asp

4 Chung, L. Y., T. C. Cheung, et al. (2001). "Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells." Life Sci 68(10): 1207-14

5 Larsson SC. Arch Intern Med. 2005;165:2683-2686. Tea Consumption and Ovarian Cancer Risk in a Population-Based Cohort

6 Touillaud MS. Dietary Lignan Intake and Postmenopausal Breast Cancer Risk by Estrogen and Progesterone Receptor Status. J. Natl. Cancer Inst. 2007 99: 475-486; doi:10.1093/jnci/djk096

7 Lampe JW. Plasma Isoflavones and Fibrocystic Breast Conditions and Breast Cancer Among Women in Shanghai, China. Cancer Epidemiol Biomarkers Prev 2007 16: 2579-2586 doi: 10.1158/1055-9965.EPI-07-0368

8 Jacobs ET. Fiber, sex, and colorectal adenoma: results of a pooled analysis. Am. J. Clinical Nutrition, Feb 2006; 83: 343 – 349

9 Pilz S. Low Serum Levels of 25-Hydroxyvitamin D Predict Fatal Cancer in Patients Referred to Coronary Angiography. Cancer Epidemiol Biomarkers Prev 2008 17: 1228-1233 Published Online First May 7, 2008. doi: 10.1158/1055-9965.EPI-08-0002

10 Talwar SA. Dose response to vitamin D supplementation among postmenopausal African American women. Amer Jou Clin Nutr 2007; 86: 1657-1662

11 Martineau AR. A Single Dose of Vitamin D Enhances Immunity to Mycobacteria. Am. J. Respir. Crit. Care Med. 176: 208-213. First published online as doi:10.1164/rccm.200701-007OC

12 Hu FB. Vitamin D and Calcium Intake in Relation to Type 2 Diabetes in Women. Diabetes Care 29: 650-656

13 Autier P, Gandini S. Arch Intern Med. 2007;167(16):1730-1737

14 Winkelmann BR, März W, Boehm BO, et al. Rationale and design of the LURIC study: a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease. Pharmacogenomics 2001;2:1–73

Back to Top

Lutein and Omega-3 Both Iportant for Eye Health in Women

By Greg Arnold, DC, CSCS, May 15, 2008, abstracted from “The influence of supplemental lutein and docosahexaenoic acid on serum, lipoproteins, and macular pigmentation”in the 2008 issue of the American Journal of Clinical Nutrition

Age-related Macular Degeneration (AMD) is the leading cause of irreversible visual impairment and blindness in the U.S.(1). The condition causes vision loss in more than 200,000 Americans every year(2) and is expected to increase to 3 million cases over the next 20 years(3). The only two known risk factors for AMD are cigarette smoking and advancing age(4). There is no cure for AMD, so preventive measures are a priority.

Fortunately, antioxidants have been found to benefit eye health (5) and AMD. Several studies over the past few years have found that lutein is important for eye health. Two mouse studies in 2006(6, 7) as well as a third study showed that low lutein and zeaxanthin levels decrease artery health(8). A 2007 study showed that 12 mg of lutein benefits eye health(9). A study in 2008(10) even showed that lutein and zeaxanthin benefit healthy eyes.

Lutein’s ability to promote eye health lies in its antioxidant properties(11, 12), which filter blue light and protect the macula from oxidative damage(13). Oxidative damage is elevated in the eye because of repeated exposure to light and the high rate of oxidative metabolism in the retina(14). This cumulative oxidative damage is thought to play a central role in the onset of AMD. Because research has shown that lutein and zeaxanthin supplementation increases blood levels of these antioxidants(15), antioxidant supplementation for eye health has become increasingly important.

Now a new study(16) that lutein and omega-3 fatty acids , also shown to benefit eye health(17), when taken together, may help eye health and AMD. In the study, 57 non-smoking women 60 to 80 years of age took one of four different supplement regimens with a nutrition energy drink (360 calories with 10 grams protein, 45 grams carbohydrate, and 14 grams fat) every day for four months. The patients took either a placebo, fish oil in the form of DHA (800 mg/day), lutein (12 mg/d plus 0.5 mg zeaxanthin), or lutein + DHA (12 and 800 mg/d, respectively). In addition to keeping dietary records using a 100-item questionnaire(18), patients underwent regular eye examinations to measure macular pigment eye density (MPOD), which has been previously used as a measure of overall eye health(19). The researchers chose older women because they tend to have an increased risk of AMD(20).

By the end of four months, the researchers found that compared to placebo, total MPOD was nearly five times greater in the lutein group and nearly three times greater in the lutein + DHA group. While the researchers expected the MPOD findings from the lutein group, they cited the results from the lutein + DHA group as “unexpected” and suggested that DHA may increase lutein uptake in the eye. They confirmed their results with previous research in the Nurses' Health Study and the Health Professionals Follow-Up Study(21), which found that those who ate fish more than four times per week had a 35% lower risk of AMD than those who ate fish less than three times per month.

For the researchers, “Lutein and DHA may aid in prevention of age-related macular degeneration.”

Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com.

Reference:

1 National Advisory Eye Council. Vision Research—A National Plan: 1999-2003, Vol. 1. A Report of the National Advisory Eye Council. Bethesda, Md: National Institutes of Health; 1999. NIH publication 98-4120

2 National Institutes of Health National Eye Institute and Prevent Blindness America. Vision Problems in the US: Prevalence of Adult Vision Impairment and Age-Related Eye Disease in America. Schaumburg, Ill: Prevent Blindness America; 2002

3 Eye Disease Prevalence Research Group. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol. 2004;122:564-572

4 Mitchell P, Wang JJ, Smith W, Leeder S. Smoking and the 5-year incidence of age-related maculopathy. Arch Ophthalmol. 2002;120:1357-1363

5 Van Leeuwen. Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA. 2005 Dec 28;294(24):3101-7

6 Wang M. Antioxidant activity, mutagenicity/anti-mutagenicity, and clastogenicity/anti-clastogenicity of lutein from marigold flowers. Food Chem Toxicol 2006; 44(9): 1522-1529

7 Choi JS. Inhibition of nNOS and COX-2 expression by lutein in acute retinal ischemia. Nutrition 2006, In Press, Corrected Proof, Available online 2 May 2006

8 Lidebjer C. Low plasma levels of oxygenated carotenoids in patients with coronary artery disease. Nutr Metab Cardio Dis 2006. In Press, Corrected Proof, Available online 30 June 2006

9 Trieschmann M. Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: The LUNA study. Exp Eye Res 2007; 84(4): 718-728

10 Stringham JM, Hammond BR, Macular Pigment and Visual Performance under Glare Conditions, Optometry and Vision Science. 2008 Feb;85(2):82-8

11 Krinsky NI. Antioxidant function of carotenoids. Free Radic Biol Med 1989;7:617–35

12 Schalch W. Carotenoids in the retina: a review of their possible role in preventing or limiting damage caused by light and oxygen. Basel, Switzerland: Birkhauser, 1992

13 Barker FM, Neuringer M, Johnson EJ, Snodderly DM, Schalch W, Koepcke W. Dietary zeaxanthin or lutein improves foveal photo-protection from blue light in xanthophyll-free monkeys. Invest Ophthalmol Vis Sci 2005;46:1770 (abstr.)

14 Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr 1995;62:1448S–61S

15 Thompson DJS. The Effect of Lutein and Zeaxanthin Supplementation on Metabolites of These Carotenoids in the Serum of Persons Aged 60 or Older. Invest. Ophthalmol. Vis. Sci. 2006 47: 5234-5242

16 Johnson EJ. The influence of supplemental lutein and docosahexaenoic acid on serum, lipoproteins, and macular pigmentation. Am. J. Clinical Nutrition, May 2008; 87: 1521 – 1529

17 Connor KM. Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis. Nature Medicine 2007. Published online: 24 June 2007; | doi:10.1038/nm1591

18 Block G, Hartman AM, Dresser CM, Carroll MD, Gannon J, Gardner L. A data-based approach to diet questionnaire design and testing. Am J Epidemiol 1986;24:453–69

19 Iannaccone A. Macular Pigment Optical Density in the Elderly: Findings in a Large Biracial Midsouth Population Sample. Investigative Ophthalmology and Visual Science. 2007;48:1458-1465. DOI: 10.1167/iovs.06-0438

20 Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr 1995;62:1448S–61S

21 Cho E, Hung S, Willett WC, et al Prospective study of dietary fat and the risk of age-related macular degeneration. Am J Clin Nutr 2001;73:209–18

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Study Uncovers How Niacin Helps Maintain Healthy Cholesterol Levels

By Greg Arnold, DC, CSCS, June 17, 2008, abstracted from “Niacin inhibits surface expression of ATP synthase â chain in HepG2 cells: implications for raising HDL” in the June 2008 issue of the Journal of Lipid Research

The American Heart Association (AHA) defines cholesterol as “a soft, waxy substance found among the (fats) in the bloodstream…[that is]…an important part of a healthy body because it's used to form cell membranes, some hormones and is needed for other functions”. It is absolutely essential to proper function of your cells(1).

But high levels of cholesterol are “a major risk factor for coronary heart disease , which leads to heart attack ”. As a result, the AHA recommends that total cholesterol levels remain below 200 mg/dL, with LDL cholesterol (“bad” cholesterol) below 70 mg/dL and HDL cholesterol (“good cholesterol”) above 40 mg/dL1.

Fortunately, a number of ways have been found to help with cholesterol health, including psyllium (2), plant sterols for both diabetics (3) and those without diabetes(4), chitosan (5), guar gum (6), rice bran oil (7), curcumin (8), fish oil (9), and soy (10). Another way to help with healthy cholesterol levels includes niacin , a vitamin known to help maintain healthy HDL cholesterol levels(11), but how it accomplishes this has remained elusive(12). The current RDA for niacin is 16 mg per day for men and 14 mg per day for women(13).

Now a new study(14) may have found just how niacin helps maintain healthy cholesterol levels. In the study, researchers discovered that niacin affects a receptor on liver cells called ATP Synthase. Specifically, niacin decreased activity of the ATP Synthase receptor by as much as 27% and also decreased HDL uptake by liver cells by 35%, allowing HDL cholesterol to remain in the blood and improve overall cholesterol levels. These results are significant because it “explain[s] how niacin's unique mechanism of action makes it a potent agent for atherosclerosis treatment .”,p> For the researchers, “The findings add to our expanding knowledge of the mechanism of niacin action on its wide range of clinical effects, including [maintaining healthy cholesterol levels]…and inflammation anti-inflammatory, anti-[clotting] and [detoxifying] effects.”

Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com.

Reference:

1 “Cholesterol” posted on www.americanheart.org/presenter.jhtml?identifier=4488

2 Moreyra, A. E., A. C. Wilson, et al. (2005). "Effect of combining psyllium fiber with simvastatin in lowering cholesterol." Arch Intern Med 165(10): 1161-6

3 Lichtenstein A. H. Rice bran oil consumption and plasma lipid levels in moderately hypercholesterolemic humans. Arterioscler. Thromb. 1994; 14:549-556

4 Jenkins DJA. Effect of plant sterols in combination with other cholesterol-lowering foods. Metabolism 2008; 57(1): 130-139

5 Hossain, S., et al., Effects of shrimp (Macrobracium rosenbergii)-derived chitosan on plasma lipid profile and liver lipid peroxide levels in normo- and hypercholesterolaemic rats. Clin Exp Pharmacol Physiol, 2007. 34(3): p. 170-6

6 Shahzadi N. Effect of guar gum on the serum lipid profile of Sprague Dawley rats. Food Sci Tech 2007: 40(7): 1198-1205

7 Most, M. M., R. Tulley, et al. (2005). "Rice bran oil, not fiber, lowers cholesterol in humans." Am J Clin Nutr 81(1): 64-8

8 Peschel D. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. Jou Nutr Biochem. In Press, Corrected Proof, Available online 18 May 2006

9 Kelley DS. Docosahexaenoic acid supplementation improves fasting and postprandial lipid profiles in hypertriglyceridemic men Am J Clin Nutr 2007;86:324 –33

10 Cho SJ. Cholesterol Lowering Mechanism of Soybean Protein Hydrolysate. Jou Agr Food Chem 2007; 55(26): 10599 – 10604

11 Carlson, L. A. 2006. Nicotinic acid and other therapies for raising high-density lipoprotein. Curr. Opin. Cardiol. 21: 336–344

12 Kamanna, V. S., and M. L. Kashyap. 2007. Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents? Am. J. Cardiol. 100: S53–S61

13 “Niacin” posted on www.nal.usda.gov/fnic/DRI//DRI_Thiamin/123-149_150.pdf

14 Zhang LH. Niacin inhibits surface expression of ATP synthase â chain in HepG2 cells: implications for raising HDL J. Lipid Res. 2008 49: 1195-1201. First Published on March 3, 2008; doi:10.1194/jlr.M700426-JLR200

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