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| Grapefruit Seed Extract / Citricidal - Treatment of Oral Infections Grapefruit Seed Extract, Aloe, and Zinc Protect against Oral Infections.
Excerpted from Hepatitis Weekly, June 1, 1998
by Salynn Boyles, Senior Editor
"Adding zinc, aloe, or grapefruit seed extracts to toothpaste may protect against viral and bacterial infections of the oral cavity, according to a report from New York City's Pace University."
The report was delivered at the 98th General Meeting of the American Society for Microbiology, held May 17-21, 1998, in Atlanta, Georgia, USA.
Over-the-counter toothpastes and mouth rinses may kill bad breath and bacteria, but most are virtually harmless against viruses. In this study researcher Milton Schiffenbauer and colleagues added zinc, aloe, and grapefruit seed extract to mouthwashes, rinses, and toothpaste in an effort to prevent disease-causing microorganisms in the mouth.
"Our findings have a significant impact on oral hygiene care and its emerging role in chronic, systemic diseases, due to the fact that many viruses found in the body enter through the mouth," Schiffenbauer said in a May 20th presentation.
Schiffenbauer noted that medical researchers have recently discovered that bacterial infections in the mouth may lead to blood clots that can bring on heart attacks and strokes. The article also noted that several studies conducted since 1989 suggest that people with periodontal disease have an increased risk of heart disease and stroke.
For the past several years, scientists in Pace University's Biology Department have conducted research on oral microbiology and viruses. Their studies found that most of a variety of oral agents tested for their antiviral properties were not effective, and some even protected viruses under certain conditions. Their research focused on two viruses(bacteriophages T1 and T7, which infect Excheria coli B that attack bacteria.
The Study
Extracts of zinc, aloe, and grapefruit were separately added to toothpaste and combined in test tubes with the viruses. The loss of phage titer, as a result of these natural additives, was observed for phage stored at room temperature(25 degrees C.), at refrigeration(4 degrees C.) and at subfreezing (-12 degrees C.) temperatures.
Grapefruit Seed Extract
T1 and T7 were totally inactivated after 10 minutes exposure at room temperature to NutriBiotic brand grapefruit seed extract (Citricidal) (undiluted and 10% dilution). An appreciable decrease in T1 titer, i.e. 85% loss, was also obtained with a crude extract of grapefruit peelings.
Zinc
Zinc totally inactivated both phages. T1 inactivation occurred after 10 minutes mixing at room temperature, whereas T7 inactivation occurred after one day storage under refrigeration. Toothpaste had no antiviral effect on T1 or T7 and actually protected the phages from inactivation at sub-freezing terperatures. However, in the presence of 1% zinc, the toothpaste had a very significant antiviral effect on both phages; total inactivation occurred after one day storage under refrigeration.
Alowe Vera
Substantial inactivation of both phages was obtained with purified aloe vera after two days of storage(day one under refrigeration, day two at subfreezing temperature), i.e. 88% and 95% loss of titer for T1 and T7, respectively.
A crude extract of aloe, strained or unstrained, had little, if any, effect on the phages. Mouthwash which contains purified aloe vera juice totally inactivated T1 and T7 after 10 minutes of mixing at room temperature. After 10 minutes of storage at room temperature, under refrigeration and in sub-freezing conditions, T1 and T7 viruses were virtually inactivated.
"This research serves as a model to investigate viral and bacterial infections of the oral cavity," Schiffenbauer said. "Pace researchers will expand their study to include other common forms of viruses that may weaken the gums and allow entry of harmful bacteria."
Grapefruit Seed Extract Information and Products are Listed Below
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 | Grapefruit Seed Extract Liquid Concentrate - 2 fl. oz. Used Grapefruit Seed Extract topically as an antiseptic wound cleaner and to treat infections of the skin.

|  |  | Grapefruit Seed Extract Liquid Concentrate - 4 fl. oz. Grapefruit Seed Extract may be used topically as an antiseptic wound cleaner and to treat infections of the skin. Internally, the concentrate is useful as a supportive treatment for a wide variety of ailments.

|  |  | Grapefruit Seed Extract 125mg - 100 Tablets Grapefruit seed extract tablets are used internally as a supportive treatment for a wide variety of ailments, including Candida infections, sore throats, intestinal upset, etc. The product is easy to swallow and eliminates the problem of bitter or unpleasant taste.

|  |  | Nutribiotic Grapefruit Seed Extract Plus 125mg - 90 Capsules NutriBiotic Grapefruit Seed Extract Plus Capsules contain 125 mg of grapefruit seed extract, equivalent to 12-15 drops of NutriBiotic GSE liquid concentrate, combined with the extracts of echinacea and artemisia annua.

|  |  | Defense Plus, NutriBiotic, w/ Grapefruit Seed Extract, Maximum Strength Immune System Support, 250mg - 90 Tablets Defense Plus with Grapefruit Seed Extract is the most powerful natural product available for enhancing the body's defense system and providing nutritional support for people with certain health concerns.

|  |  | Nutribiotic First Aid Skin Spray - 4 fl. oz. (w/ Grapefruit Seed Extract & Tea Tree Oil) Grapefruit Seed Extract acts as a broad spectrum antiseptic and antibiotic. Keeps the wound clean and helps to speed healing with Grapefruit Seed Extract & Tea Tree Oil.

|  |  | NutriBiotic Skin Ointment, w/ Grapefruit Seed Extract & Lysine, 0.5 oz. NutriBiotic Skin Ointment with GSE can be used topically for such things as scrapes, scratches and cuts. NutriBiotic Skin Ointment with GSE can also be used on the lips and in the mouth on cold sores and canker sores.

|  |  | Skin Cleanser, Non Soap with Grapefruit Seed Extract, Original - 16 fl. oz. Non-Soap Skin Cleanser will clean skin and remove dirt and oil as well as harsher soaps but will not dry and damage the skin in the process. Original NutriBiotic NonSoap Skin Cleanser contains CITRICIDAL, a natural standardized extract of grapefruit seed.

|  |  | Nutribiotic Nasal Spray, with Grapefruit Seed Extract - 1 fl. oz. Nasal Spray is useful to aiding many conditions. During allergy season it helps to re-moisturize the nasal passages and clean them of dust, dirt, dander and other allergens. The nasal spray is also useful during a bout of sinusitis, or inflammation and infection of the sinus passages.

|  |  | NutriBiotic Hand & Body Lotion - 8 fl. oz. w/ Grapefruit Seed Extract & Aloe Vera Hand & Body Lotion has been laboratory proven to kill up to 99.9% of bacteria within 1 minute after application.

|  |  | Deodorant Stick, with Grapefruit Seed Extract, Unscented - 2.6 oz. Grapefruit Seed Extract deodorant actually helps to eliminate odor causing bacteria instead of just masking it with a perfume.

|  |  | Nutribiotic Dental Gel, w/ Grapefruit Seed Extract, Natural Flavoring, 4.5 oz. Our Dental Gel uses natural ingredients, is only mildly abrasive, and contains ingredients known to support healthy teeth and gums. It is free of fluoride, which has stirred some controversy due to its toxicity.

|  |  | NutriBiotic Body & Foot Powder, w/ Grapefruit Seed Extract, All Natural - 4 oz. Grapefruit Seed Extract Body and Foot Powder is actually a multi-purpose product. It is extremely pure and mild and therefore may be used all over the body on adults as well as children.

|  |  | NutriBiotic Bubble Bath, with Grapefruit Seed Extract, 16 fl. oz. NutriBiotic Fresh Fruit Scent Bubble Bath makes the bath experience fun for grownups and kids alike. Our product provides mounds of bubbles and is mild to prevent irritation of the skin and urinary tract.

|  |  | Travelers Friend Drinking Water Treatment - 0.3 fl. oz. (10ml) NutriBiotic Traveler's Friend is the only safe, non-toxic water purifier available today. Perfect for camping, boating, fishing and travel to areas where the food and drinking water are questionable.

|  |  | NutriBiotic Ear Drops, w/ Grapefruit Seed Extract - 1 fl. oz. NutriBiotic Ear drops are an excellent topical treatment for ear aches, swimmer's ear and over-production of wax.

|  |  | Germbuster Grapefruit Seed Extract w/ Echinacea - 0.3 fl. oz. Germbuster Grapefruit Seed Extract provides protection from germs that your body needs. Ideal for travel, vacation, camping, anywhere there's a crowd of people and the potential for germs.

|  |  | MouthFresh Natural Mouthwash & Gargle - 12 fl. oz. MouthFresh Natural Mouthwash refreshes Breath, Promotes Healthy Gums, Soothes Sore Throats, Sweetened Naturally with Stevia.

|  |  | TheraClear Anti Parasite Formula - 120 Capsules A regular natural detoxification program including TheraClear Anti Parasite Formula and a colon cleanser to promote proper elimination has been recommended by various naturopaths.

|  |  | Royal Jelly Eye Cream (14 g) .50 oz. Burt's Bees Royal Jelly Eye Creme provides long-lasting, moisturizing protection and can be worn under make up or as an overnight treatment.

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