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Female Regularity, Shenrong Dingkun (60 Capsules/bottle)
Female Regularity, Shenrong Dingkun is made of ginseng, deer horn, carthamus, millettia, notoginseng, common peony root, prepared rehmannia root, Chinese angelica root, atractylodes, wolfberry, scute, cyperus, mother wort, cnidium, de-glued antler powder, donkey hide glue and corydalis.
Chinese medicine uses this time-honored formula to tonify the Qi and blood, activate female hormone, maintain healthy uterus smooth muscle tension, promotes gynecological regularity and postpartum recovery. It is also an analgesic.
Direction for Use:
As a dietary supplement, take 3~5 capsules 3 times daily. Not recommended for use by pregnant woman. Store in a dry and cool place, out of the reach of children.
Balanceuticals formulas are formulated and manufactured according to the most stringent quality standards and the most up-to-date achievements in traditional Chinese medicine. They are screened for quality and safety by a specialist group at the China Academy of Traditional Chinese Medicine, the highest research institution for traditional Chinese medicine.
Summary of Modern Studies on Shenrong Dingkun (Female Regularity¢â) Capsule
Chinese Use: Deficiency of both qi and blood, irregular menses, dkysmenorrhea, sterility.
Modern studies on pharmacodynamics reveal that this product yields actions of activity similar to female sex hormone, remitting the tension of smooth muscle of uterus, analgesia, strengthening the phagocytosis of the organism.
1. Activity similar to female sex hormone: The method of increasing the weight of female sex organ by estrogen is adopted. Young female rats are used and assigned to experimental and control group. This product is given by gastric perfusion 6000mg/kg. The control group is administered excipient powder in same volume (1 ml) for gastric perfusion. The positive control group is given 4mg of stilbestrol as a reference dissolved in 0.2ml vegetable oil, once every other day for 5 times (10 days). The animals are anatomized 3 days after suspension of the remedy. The weights of ovary and uterus /100g body weight are compared among groups. The weight in the experimental group is 161(mg/100g body weight); the blank control group is 131, the stilbestrol group is 254, with very significant difference among the groups, indicating that this product possesses the activity similar to female sexual hormone. Under the microscope, the endometrium of rat is thickened, with cells arranged evenly in two layers with more acinus in larger volume and near to the endometrium. The acini are in secreting status. In the ovary, there are ova of primary, secondary and mature stages, developed steadily in order. This offers a pharmacological evidence for the action of treating irregular menstruation, underdeveloped sex organs and sterility with this product. It is also evident that, unlike the strong action of stilbestrol, this product demonstrates that the compound recipe of TCM yields persistent and mild actions.
2. Remission of tension of smooth muscle of uterus: In the solution of this product (1:5) 0.5 ml or 1 ml, the in vitro rat uterus doesn¡¯t show tension reaction. After Magnus bath for 5 minutes, 0.125¥ìpituitrin is added, the uterus contracts. When the medicinal and nutritional solution are removed and the uterus washed, then equal volume of this product (1:5) 1 ml and pituitrin 0.125¥ìare added , the uterus contracts, with a distance 5 mm less than the former one.
3. Analgesia: One hour before the gastric perfusion administration of this product 0.3g/20g chemical stimulation is given in mice. Aspirin is given for the positive control group in the dose of 180mg/kg, while the blank control group reveals 212 paroxysmal pain within 5 ~10 minutes, being 17.7 in average per mouse. In the aspirin group, there are 81 within 5~10 minutes, being 8.1/mouse. The experimental group reveals 80 in 5~10 minutes, being 8.0/mouse. The inhibition of paroxysmal pain being 50% of the control group, indicating that this product yields marked analgesic effect.
4. Increase of phagocytosis: This product is prepared as feeding fragments and administered to mice in the dose of 4.8g/kg. The control group is given the same fragments without this product for 7 consecutive days. Then, sterilized broth is injected peritoneally. After 22 hrs, another injection containing chicken RBC suspension 0.5ml /(5¡¿106) is administrated. After 40 minutes, the animals are killed and smears made of abdominal fluid, and stained. Phagocytosis index is determined under the microscope. The control group reveals a phagocytosis rate of 17.32¡¾1.5%, phagocytic index 1.44 ¡¾0.15.That of the experimental group are 32.76¡¾1.80% and 1.50¡¾0.15 respectively, with very significant difference. The phagocytic capacity is markedly increased, but the phagocytic index shows no significant difference.
Clinically, this product was used in menstrual disorders, sterility, and post partal deficiency.
1. Menstrual disorders: Mainly manifesting irregular menstrual cycle, profuse menstrual bleeding, light color and loose texture, lumbago, scanty blood, pink and clear blood like water, or with coagulated clots, leukorrhea, rubrorrhea, phthisis, hectic fever, massive hemorrhage, leaking blood, bloody fainting, bloody collapse, delayed or prior menstruation, menolipsis prior to climacteric period, functional uterine bleeding, uterine bleeding during puberty, climacteric period. This product is indicated for the above disorders.
2. Sterility: This product is indicated for non-organic sterility.
3. Postpartum deficiency: This product is indicated for lassitude after delivery, loss of appetite, insomnia, forgetfulness, lower abdominal pain, and lingering lochia.
Excerpt from A Guide to TCM Products, China Academy of Traditional Chinese Medicine, 2003
Female Regularity, Shenrong Dingkun (60 capsules/bottle)
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