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DHEA General Information
DHEA Uses & Scientific Evidence For
DHEA Dosage Information
DHEA Safety & Interaction Information
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DHEA General Information
DHEA is the acronym for dehydroepiandrosterone, a hormone that is produced by the adrenal glands, and is the base from which other key substances such as the hormones testosterone, progesterone, and Corticosterone can be derived. DHEA is actually an intermediate in the biosynthesis of testosterone and estrogen taking place in the adrenal glands. As we age, the levels of certain hormones decline, especially dehyroepiandrosterone or DHEA. It begins to decline or become deficient after the age of 30 with about a 50% decline by the age of 40 and about 85% decline by the age of 70. DHEA deficiency is a normal thing the body does.
DHEA was first identified in 1934 and was sold over the counter mainly as a weight loss aid until the late 1980s. Then the federal Food and Drug Administration (FDA) classified DHEA as a drug, making it available by prescription only. The FDA reversed itself in 1994, reclassifying DHEA as a dietary supplement obtainable without a prescription.
Originally marketed as a weight loss supplement, DHEA is now promoted as being beneficial for treating a wide variety of medical conditions, including cancer, heart disease, Alzheimer's, and AIDS. It is also purported to have anti-aging qualities.
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DHEA Uses & Scientific Evidence For
Taking DHEA supplements can help prevent cancer, arterial disease, multiple sclerosis, and Alzheimer’s disease, and may be of benefit for those with lupus and osteoporosis. DHEA helps boost the immune system and enhances memory as well. In clinical trials on genetically obese and normal animals, DHEA demonstrated anti-obesity (fat reducing) properties, and serum cholesterol reducing actions.
In January of 2007 from Medscape Family Medicine reported that DHEA may reduce the incidence of chronic disease and has demonstrated inhibition of inflammation along with associated epithelial hyperplasia, carcinogens, and artherosclerosis. Results of research on the treatment effects of DHEA supplementation have been mixed, however.
In one placebo-controlled trial of older adults with a reduced level of serum DHEA, supplementation of DHEA at a dose of 50 mg/day was associated with reduced levels of fat and insulin.
In 2006 Reuters Health Information reported that DHEA Replacement Improves Bone Mineral Density in Older Adults. This the report stated, “DHEA-sulfate levels increased five-fold in patients randomized to DHEA treatment, the authors report, whereas levels remained stable in the placebo group. DHEA replacement appeared to have beneficial effects on BMD of the total hip and trochanter and shaft sub-regions but not of the femoral neck, the results indicate. Lumbar spine BMD did not change significantly overall.”
A 1994 study by researchers at the University of California, San Diego looked at 30 middle-age men and women who took 50 mg of DHEA a day for three months. The test subjects generally reported an improved sense of well-being, increased energy, enhanced sex drive, and an improved ability to deal with stress. The results were widely reported by the mass media, with several referring to DHEA as the "fountain of youth hormone."
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DHEA Dosage Information
It is best to read and follow product label directions before taking DHEA in your daily diet. 7-Keto DHEA is a derivative of DHEA that is not converted into estrogen or testosterone, and is good for women concerned about breast cancer, and for men concerned with prostate cancer. 7-Keto DHEA is a very good alternative to DHEA that offers the same benefits. For best results, it is beneficial to supplement with vitamin C, vitamin E and selenium to help prevent damage to the liver. DHEA does come in many forms, tablets, capsules and such.
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DHEA Safety & Interaction Information
If you are pregnant or nursing, please consult your health care practitioner before taking this product. Laboratory studies have shown that high DHEA doses may cause liver damage. DHEA side effects can concern women, who may experience excess facial hair growth, which may be avoided by starting with lower daily doses.
Studies have shown DHEA may increase the risks of prostate cancer in men and endometrial cancer in women. It is suggested that before taking DHEA supplements, individuals should have a blood test to determine existing DHEA and other hormone (testosterone or estrogen) levels. Men taking the supplement should have regular PSA tests and women should have periodic mammograms since DHEA may promote the growth of breast cancer.
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