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Herbal Remedies Natural Health Newsletter, October 2008, Issue 285

Herbal Remedies October 2008 Natural Health Newsletter Issue 285 Sponsored by www.HerbalRemedies.com Toll Free for orders 1-866-467-6444 Issue Editor - Heather Bowman

Herbs - Vitamins - Minerals - Magnetics - Candles - Aromatherapy - Holiday Gifts - Bath & Beauty - Essential Oils - Natural Pet Care - Condition & Ailment Guide - Women's Health - Men's Health - Weight Loss - Health Books Omega-3 Fats Hold Promise for Mental Health - Click here for full story. Green Tea Benefits Stomach and Colon Health - Click here for full story. Study Re-Confirms Pycnogenol’s Role in Joint Health - Click here for full story. Be a Liver Lover: Alpha Lipoic Acid and Other Supplements Offer Hope - Click here for full story. Calcium Found to Recude Stroke Risk - Click here for full story. Herbal Remedies has 2 partner sites be sure to check them out as well: Magnetic Therapy Magnets , and Natural Hair Loss Remedies Be sure to check out our Overstocked clearance items! OVERSTOCKED Give your skin a natural glow with Burt's Bees Products. We are your #1 Headquarters for your complete line of Burt’s Bees Products for that all around natural glow!! Herbal Remedies has four new vendors be sure to check them out: MacroLife Naturals, Inc. , PowerBar Nutritional Bars, Sante Active , and Planetary Herbals Products Spotlight – Want sun kissed skin without the UV or applying messy creams? Elusun self tanning pill supplements help you maintain a healthy golden glow without exposing your skin to the harsh rays of the sun. Using the richest source of natural carotene's, Elusun works from the inside out to advance the skin's natural pigmentation process, promoting an even head-to-toe tan with no messy bronzing gels or creams. This unique three-in-one formula also contains Vitamins C and E - valuable antioxidants known to reverse the signs of aging, as well as Borage oil to help your skin maintain proper moisture levels. Stay tan long after the sun goes down with Elusun self-tanning supplements. Just because summer has faded doesn't mean your tan has to. Current Event News: Bacterial Infections and the emerging antibiotic-resistant bodies! Bacteria cause disease in two ways: they release toxins that harm and kill body cells, and they provoke the immune system, leading to inflammation, which can in itself be harmful. The body's first reaction to a bacterial invasion is a general inflammatory reaction. Blood vessels in the area of the infection widen to increase the supply of white blood cells that fight infection. Blood proteins, called complement, are released into the system. Complement either kills the bacteria directly or attracts immune cells called phagocytes, which ingest and kill the bacteria. The body then produces more immune cells, including white blood cells called T cells, which kill foreign substances in the body. T cells stimulate other white blood cells called B cells to secrete specific antibodies. Antibodies are molecules that the body's immune system uses to identify a particular invader. Over a person's lifetime, the immune system develops millions of antibodies. In response to a bacterial invasion, the antibodies bind to bacteria and then attract complement and phagocytes, which kill the bacteria. Bacterial infections can disrupt normal intestinal flora, reduce vitamin and mineral supplies, and compromise immune responses. A healthy immune system can prevent or neutralize bacterial infections. In addition, many nutrients have been shown to help strengthen the immune system and inhibit bacterial infection by acting as natural alternative to antibiotics. Check Out our Back to School Wellness Savings with our Coupon Savings and with these kind of prices you can afford to stock up! QUESTIONS AND ANSWERS Q: Subject: Hello Hi In the Acai Juice by NOW Foods what kind of sugar is added in the 2grams of sugar in the ingredients? Thank you for your time. A: Dear Customer, The 2grams of sugars in Acai by NOW foods isn't an added sugar it is from the berries naturally occurring sugars. Ingredients: Acai Juice, Triple Filtered Water, Blueberry Juice Concentrate, Raspberry Juice Concentrate, Pomegranate Juice Concentrate, Citric Acid, Natural Flavor and Potassium Sorbate (as a preservative). Contains no: added sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or artificial colors/flavors. Thank you and All my best, Thank you for your interest in Herbal Remedies.com and the opportunity to serve you. Heather * The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding you or your child's condition. Informational material and representations have been provided by the manufacturers of the listed products. Our Sponsors Enter coupon code "NL102908" when checking out to obtain discounts on your next purchase from http://www.HerbalRemedies.com. How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.49 automatic shipping discount for orders over $95. The more you order the more you save!!! All previous sales and previous sale items excluded , only one coupon code per order

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Omega-3 Fats Hold Promise for Mental Health By Greg Arnold, DC, CSCS, September 23, 2008, abstracted from “Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk” in the September 2008 issue of the American Journal of Clinical Nutrition The incidence of Alzheimer Disease (AD) has doubled since 1980, currently affecting just under 5 million Americans, and expected to affect 16 million by 2050(1). The condition currently costs our healthcare system over $100 billion each year(2). Fortunately, there are some simple ways to help maintain mental health, including eating apples(3), drinking green tea (4), taking vitamin E (5) and grape extract (6). A 2006 study on fish oil’s ability to maintain mental health (7) found that fish oil increases brain chemicals and “might thus be useful and offer therapeutic benefit in treating [AD]” . Another 2006 study(8) found that omega-3 fats have “positive effects…in a small group of patients with very mild AD”. Now a new study(9) has found more evidence that fish oil may help maintain mental health. In the study, 1214 patients from the Three-City Study (3CS) underwent a physical exam and neuropsychological testing(100, completed a questionnaire on depression (11), and provided blood samples. They were then followed up four years later. The researchers found that regular fish consumption (eating fish or seafood at least once per week) decreased AD risk by 38%. Blood levels of EPA and DHA were 25% and 9.5% higher in patients without AD, resulting in 34% and 24% reduced risks of AD. Finally, they found that depression is an independent risk factor for dementia, and low EPA levels increase the risk of dementia in depressed patients by 52%. For the researchers, “Our results provide evidence that both lower plasma EPA and higher depression may increase the risk of dementia.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 Hebert, LE; Scherr, PA; Bienias, JL; Bennett, DA; Evans, DA. “Alzheimer Disease in the U.S. Population: Prevalence Estimates Using the 2000 Census.” Archives of Neurology August 2003; 60 (8): 1119 – 1122 2 Ernst, RL; Hay, JW. “The U.S. Economic and Social Costs of Alzheimer’s Disease Revisited.” American Journal of Public Health 1994; 84(8): 1261 – 1264 3 Lee, C. Y. (2004). "Protective Effects of Quercetin and Vitamin C against Oxidative Stress-Induced Neurodegeneration." Journal of Agricultural and Food Chemistry 52: 7514-7517 4 Tan J. Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice J. Neurosci. 2005 25: 8807-8814 5 American Academy of Neurology 60th Anniversary Annual Meeting 15 April 2008, Poster Sessions III: Aging and Dementia: Clinical II [P03.076] Vitamin E Use Is Associated with Improved Survival in an AD Cohort Authors: V. Pavlik, R. Doody, S. Rountree, E. Darby 6 Wang J. Grape-Derived Polyphenolics Prevent Aâ Oligomerization and Attenuate Cognitive Deterioration in a Mouse Model of Alzheimer's Disease. Journal of Neurosci 2008; 28(25):6388-6392; doi:10.1523/JNEUROSCI.0364-08.2008 7 Wurtman RJ. Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally. In Press, Corrected Proof, Available online 21 April 2006 in Brain Research 8 Freund-Levi Y. Omega-3 Fatty Acid Treatment in 174 Patients With Mild to Moderate Alzheimer Disease: OmegAD Study: A Randomized Double-blind Trial. Arch Neurol 2006;63:1402-1408 9 Samieri C. Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk Am J Clin Nutr 2008;88:714 –21 10 The 3C study group. Vascular risk factors and risk of dementia: design of the Three-City Study and baseline characteristics of the study population. Neuroepidemiology 2003;22:316 –25 11 Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1977;1:385– 401

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Green Tea Benefits Stomach and Colon Health By Greg Arnold, DC, CSCS, August 7, 2008, abstracted from “Effects of Aqueous Green Tea Extract on Activities of DNA turn-over enzymes in cancerous and non-cancerous human gastric and colon tissues” in the May/June 2008 issue of Alternative Therapies After water, tea is the second most commonly consumed beverage in the world(1). The health effects of green tea are plentiful, including helping with blood vessel health(2), liver health (3), heart health(4), heart disease risk(5), mental health (2005(6) and 2006(7) studies), detoxification (8), digestive health (9), and lymph node health (10). The component of green tea responsible for all of these health effects is a category of antioxidants called catechins , specifically epigallocatechin-3 gallate (EGCG), epicatechin-3 gallate, epigallocatechin, and epicatechin. EGCG is suggested to be a stronger antioxidant than both vitamins E and C (11). Now a new study(12) has found that green tea may benefit stomach and colon health , including stomach and colon cancer. Stomach cancer is forecasted to cause nearly 11,000 deaths in 2008(13) and colon cancer is forecasted to cause nearly 50,000 deaths in 2008(14). Previous research has shown that green tea helps colorectal health(15). Building on these findings, researchers took six cancerous and non-cancerous samples of stomach tissue and seven cancerous and non-cancerous colon tissues and exposed them to three different concentrations of green tea extract (0.05%, 0.5%, and 1.25%) for one hour. They found that green tea increased activity of ADA (Adenosine Deaminase) by as much as 358% in non-cancerous stomach tissues and 266% in non-cancerous colon tissues. ADA is an enzyme found in highest amounts in immune system cells called lymphocytes which form the immune system (16). Conversely, ADA activity decreased in the cancerous stomach and colon tissues. The researchers also looked at another enzyme that is a suggested marker for stomach cancer when decreased in the body17. Xanthine oxidase (XO), increased its activity in both cancer and non-cancerous tissues when exposed to green tea extract, increasing by 265% in non-cancerous stomach tissues and 273% in cancerous stomach tissue. For the researchers, “Our data suggest that green tea may support the medical treatment of stomach and colon cancer.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 Kris-Etherton PM, Keen CL. Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health. Curr Opin Lipidol. 2002;13:41-49 2 Mukhtar H, Ahmad N. Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr 2000; 71: 1698S-1702S 3 Zhang XH. Tea drinking and the risk of biliary tract cancers and biliary stones: A population-based case-control study in Shanghai, China. Int Jou Cancer 2006; 118(12): 3089-3094 4 Tsuji I, Nishino Y, Ohkubo T, et al. A prospective cohort study on National Health Insurance beneficiaries in Ohsaki, Miyagi Prefecture, Japan: study design, profiles of the subjects and medical cost during the first year. J Epidemiol. 1998;8:258-263 5 Coimbra S. Green tea consumption improves plasma lipid profiles in adults. Nutr Res 2006; 26(11):604-607 6 Tan J. Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice J. Neurosci. 2005 25: 8807-8814 7 Shinichi Kuriyama S. Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project Am. J. Clinical Nutrition, Feb 2006; 83: 355 – 361 8 Chow, H; Hakim, I; et al. Modulation of Human Glutathione S-Transferases by Polyphenon E Intervention, Cancer Epidemiology Biomarkers and Prevention, 16, 1662-1666, August 1, 2007 9 Lee, K. M., M. Yeo, et al. (2004). "Protective Mechanism of Epigallocatechin-3-Gallate against Helicobacter pylori-Induced Gastric Epithelial Cytotoxicity via the Blockage of TLR-4 Signaling." Helicobacter 9(6): 632-42 10 Shanafelt TD. Clinical effects of oral green tea extracts in four patients with low grade B cell malignancies. Leukemia Research, Available online December 1, 2005 11 Siddiqui IA. Anitoxidants of the beverage tea in promotion of human health. Antioxidant Redox Signal 2004; 6(3): 571-582 12 Egruder IB. Effects of Aqueous Green Tea Extract on Activities of DNA turn-over enzymes in cancerous and non-cancerous human gastric and colon tissues. Alt Ther Health Med 2008; 14(3): 30-33 13 “What Are The Key Statistics About Stomach Cancer?” posted on http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_are_the_key_statistics_for_stomach_cancer_40.asp 14 “What Are They Key Statistics For Colorectal Cancer?” posted on http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_are_the_key_statistics_for_colon_and_rectum_cancer.asp 15 Yong G. Prospective Cohort Study of Green Tea Consumption and Colorectal Cancer Risk in Women. Cancer Epidemiol Biomarkers Prev 2007 16: 1219-1223 doi: 10.1158/1055-9965.EPI-07-0097 16 “ADA” posted on http://ghr.nlm.nih.gov/gene=ada 17 Linder N. Decreased xanthine oxidoreductase is a predictor of poor prognosis in early-stage gastric cancer. J Clin Pathol 2006; 59(9): 965-971

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Study Re-Confirms Pycnogenol’s Role in Joint Health By Greg Arnold, DC, CSCS, September 12, 2008, abstracted from “Effect of Pine Bark Extract (Pycnogenol®) on Symptoms of Knee Osteoarthritis” in the August 2008 issue of Phytotherapy Research Osteoarthritis is the nation’s leading cause of disability, limiting everyday activities for 16 million Americans. The condition results in 750,000 hospitalizations and costs our healthcare system over $51 billion each year(1). The Center for Disease Control estimates that the number of people aged 65 or older with arthritis will more than double, from 15.7 million in 2002 to 33.3 million in 2030(1). There are several natural ways to help maintain joint health, including antioxidant intake(2), fruit consumption such as pomegranates (3) and glucosamine with chondroitin (4). Now a new study(5) has found that Pycnogenol may benefit joint health. Previous research has shown that Pycnogenol is beneficial for lower leg swelling(6), venous ulcers(7), venous leg circulation(8), mental health (9) and healthy levels of inflammation (10). An April 2008 study showed that Pycnogenol helps inflammation levels in knee arthritis (11). Building on these findings, 100 patients with osteoarthritis were given either 150 mg of Pycnogenol or placebo per day for three months. During this time, they reported any changes in their anti-inflammatory medication (NSAIDs) use. They also completed the Western Ontario and McMasters University (WOMAC)(12) questionnaire every two weeks and reported pain symptoms every week, using a pain rating scale. Improvements in WOMAC scores reflected improvements in overall function(13). At the end of three months, WOMAC scores in the Pycnogenol group were 12% higher than in the placebo group (56 vs. 50). Pain symptoms were 29% lower in the Pycnogenol group by the end of one month and remained statistically significant by the end of the study (8% lower, p = 0.07)) than the placebo group. Regarding medication use, 62% of patients in the Pycnogenol group used the same level of medication compared to 82% in the placebo group, while 38% in the Pycnogenol group decreased their dosage compared to 10% in placebo group (8% of placebo patients increased their dosage). For the researchers, “Pycnogenol offers an interesting alternative to treatment of early knee OA with NSAIDs or analgesics because of its low rate of unwanted effects and its efficacy.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 “Targeting Arthritis: Reducing Disability for 43 Million Americans” posted on the CDC Website www.cdc.gov/nccdphp/aag/aag_arthritis.htm 2 Pattison DJ. Dietary beta-cryptoxanthin and inflammatory polyarthritis: results from a population-based prospective study. Am J Clin Nutr. 2005 Aug;82(2):451-5 3 Ahmed S. Punica granatum L. Extract Inhibits IL-1(beta)-Induced Expression of Matrix Metalloproteinases by Inhibiting the Activation of MAP Kinases and NF-(kappa) B in Human Chondrocytes In Vitro. J Nutr. 2005 Sep;135(9):2096-102 4 Richy F. Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis. Arch Intern Med. 2003 Jul 14;163(13):1514-22 5 Cesar P. Phytother. Res. 22, 1087–1092 (2008) Published online 20 June 2008 in Wiley InterScience DOI: 10.1002/ptr.2461 6 Belcaro G. Prevention of venous thrombosis and thrombophlebitis in long-haul flights with pycnogenol. Clin Appl Thromb Hemost. 2004 Oct;10(4):373-7 7 Belcaro, G., M. R. Cesarone, et al. (2005). "Venous ulcers: microcirculatory improvement and faster healing with local use of pycnogenol((r))." Angiology 56(6): 699-705 8 Cesarone MR. Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study. Clin Appl Thromb Hemost 2006; 12(2): 205-12 9 Trebaticka J. Treatment of ADHD with French maritime pine bark extract, Pycnogenol®). Eur Child Adolesc Psychiatry. 2006 May 13; [Epub ahead of print] 10 Grimm T. Inhibition of NF-êB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol) Journal of Inflammation 2006, 3:1 (27 January 2006) 11 Belcaro G. Treatment of osteoarthritis with Pycnogenol®. The SVOS (San Valentino osteo-arthrosis study). evaluation of signs, symptoms, physical performance and vascular aspects. Phyto Res 2008; 22: 518-523. Published Online: Apr 2 2008 8:56AM DOI: 10.1002/ptr.2376 12 Bellamy N. 1995. WOMAC Osteoarthritis Index. A User’s Guide, 2nd edn. Victoria Hospital: London, Ontario. 13 “WOMAC Osteoarthritis Index” posted on www.womac.org/womac/

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Be a Liver Lover: Alpha Lipoic Acid and Other Supplements Offer Hope Republished with the permission from Author James J. Gormley, American Chronicle, September 29, 2008. The Gormley Files: http://thegormleyfiles.blogspot.com/ Quick: what is the largest organ inside your body that weighs about three pounds, is shaped like a football that´s flat on one side and is located under your ribs on your right side? If you guessed the liver, you´re right. Although it may not be a pretty organ it is an extremely important one that has a month-long health observance named after it by the American Liver Foundation (www.liverfoundation.org), called Liver Awareness Month. Reasons to love our liver abound since this organ does all of the following, and more: saves up energy; makes bile to help break down food; keeps pollution from hurting us; stops cuts from bleeding too long; kills germs; gets rid of toxic chemicals; and helps build muscle. According to the foundation, liver disease affects one in 10 Americans, or about 30 million people — including children. Liver disease begins with inflammation . If left untreated, especially over time, inflamed liver tissue starts to scar or become fibrous, which is called fibrosis. If fibrosis is not treated or healed, irreversible damage can occur, called cirrhosis ; this can lead to liver cancer . If the liver loses most or all of its function, a life-threatening condition called liver failure can result. To make matters worse, there is also hepatitis C , a disease of the liver that is caused by the hepatitis C virus, or HCV. While it is fortunate that 15 to 40 percent of people who contract HCV are able to successfully fight off the virus within the first six months, sadly most of the patients who are not able to get rid of the virus wind up developing a long-term, chronic hepatitis C infection. One of the most common reasons for liver transplants, more than four million Americans have been infected with hepatitis C and the virus is responsible for 8,000 to 10,000 deaths every year. New Hope Emerges: Nutritional Supplementation In recent years, enlightened medicine has brought popularity to a variety of botanical liver lovers, including milk thistle , which has been used for what we now know as liver disease since the 12th century. Today, research often attributes milk thistle´s liver supportive effects to a compound complex in milk thistle, called silymarin , which is extracted from the milk thistle seed. Other nutrients and herbal extracts that have attracted scientific interest, of late, in liver protection include: selenium , zinc , probiotics and branched-chain amino acids . One nutrient, however, that has been the subject of research and which shows the greatest promise for liver health has curiously not yet attained the level of popularity enjoyed by milk thistle; it is: alpha lipoic acid . Alpha lipoic acid (or ALA) was first discovered by University of Illinois enzymologist Irwin Gunsalus in 1948 and described and characterized by University of Texas biochemist Lester J. Reed in March 1951. It is a natural substance that, according to ALA pioneer Burt Berkson, M.D., in the December 2007 edition of the Townsend Letter for Doctors and Patients, is the "rate-limiting factor for the production of energy from carbohydrates." In other words, without alpha lipoic acid we could not obtain energy from the food we eat and we could not stay alive. The first large-scale human clinical studies using alpha lipoic acid in the U.S. were conducted by Berkson, Frederick C. Bartter, M.D., and other scientists at the National Institutes of Health (NIH) in the 1970s. The researchers gave the nutrient to 79 people with severe liver damage; 75 of those, according to Berkson, recovered full liver function. More recently, in 1999 Berkson published three case reports using a triple- antioxidant supplement regimen in patients with liver disease, including chronic hepatitis C infection. After several months of treatment with a combination of alpha lipoic acid, selenium and silymarin, all three patients recovered most or all of their liver function, avoided liver transplantation and went on to live healthy, productive lives free of the symptoms of liver disease. From 2006 to 2008, a number of studies in humans and animals have shown that alpha lipoic acid can provide important improvements in the following: recovery following liver surgery; protection from chemotherapy side effects and chemical poisoning; liver regeneration; and protection against liver and kidney damage from acetaminophen-containing drugs (e.g., Tylenol, Anacin-3 and Percocet). Considering that acetaminophen poisoning sends over 56,000 people to emergency rooms each year in the U.S., these study results are all the more impressive. It doesn´t hurt, of course, that alpha lipoic acid also helps in the areas of nerve health (e.g., diabetic neuropathy), metabolic health (e.g., insulin resistance and weight control) and brain health. In an industrialized society heavily burdened by pollution and toxic chemicals, alpha lipoic acid has emerged, and rightly so, as a nutritional beacon of hope for many. *The above mentioned branded products are being used for Herbal Remedies promotional use and not those of the Authors. References American Liver Foundation. October is Liver Awareness Month [press release]. September 17, 2008 (www.liverfoundation.org). Website accessed September 27, 2008. American Liver Foundation. The progression of liver disease [fact sheet]. Website accessed September 27, 2008 (www.liverfoundation.org/education/info/progression). Gormley J. Powerful antioxidant for liver protection and body detoxification: milk thistle. Better Nutrition 58(2):56-61, 1996. Berkson BM. Alpha lipoic acid and liver disease. Townsend Letter. December 2007. Reed LJ. From lipoic acid to multi-enzyme complexes. Protein Sci 7:220-224, 1998. Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C; combination of alpha lipoic acid (thioctic acid), silymarin and selenium: three case histories. Med Klin (Munich) 94 (Suppl 3):84-89, 1999. Berkson BM et al. The long-term survival of a patient with pancreatic cancer with metastases to the liver after treatment with the intravenous alpha lipoic acid/low-dose naltrexone protocol. Integ Cancer Ther 5(1):83-89, 2006. Dünschede F et al. Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by alpha lipoic acid in humans. World J Gastroenterol 12(42):6812-6817, 2006. Dudka J. Decrease in NADPH-cytochrome P450 reductase activity of the human heart, liver and lungs in the presence of alpha lipoic acid. Ann Nutr Metab 50(2):121-125, 2006. Dünschede F et al. Protection from hepatic ischemia/reperfusion injury and improvement of liver regeneration by alpha lipoic acid. Shock 27(6):644-651, 2007. Dünschede F et al. Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model. World J Gastroenterol 13(27):3692-3698, 2007. Anandakumar PP et al. Antioxidant DL-alpha lipoic acid as an attenuator of adriamycin induced hepatotoxicity in rat model. Indian J Exp Biol 45(12):1045-1049, 2007. Abdel-Zaher AO et al. The potential protective role of alpha-lipoic acid against acetaminophen-induced hepatic and renal damage. Toxicology 243(3):261-270, 2008. CBC News. Use of Tylenol-type pain relief in babies linked to asthma: study. September 19, 2008 (website accessed September 28, 2008: www.cbc.ca/health/story/2008/09/19/asthma-child.html). Becić F et al. Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy. Med Arh 62(1):45-48, 2008. Pershadsingh HA. Alpha-lipoic acid: physiologic mechanisms and indications for the treatment of metabolic syndrome. Expert Opin Investig Drugs 16(3):291-302, 2007. Hager K at al. Alpha-lipoic acid as a new treatment option for Alzheimer´s disease: a 48-months follow-up analysis. J Neural Transm Suppl 72:189-193, 2007.

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Calcium Found to Recude Stroke Risk By Greg Arnold, DC, CSCS, August 11, 2008, abstracted from “Dietary Calcium Intake and Risks of Stroke, Its Subtypes, and Coronary Heart Disease in Japanese" published online ahead of print July 17, 2008 in Stroke In the United States alone, someone has a stroke every 45 seconds and someone dies of stroke every three minutes. As the third cause of death among Americans ( cancer and heart disease are the leading causes), stroke costs our healthcare system $57 billion each year(1). Alternative methods to help support heart health include vitamin D (2) and B-vitamins (3) like folic acid (4). Now a new study(5) has found that calcium , known mostly for bone health but also found to help with blood sugar health(6) and colon health(7), may also help support heart health as it pertains to stroke. A previous study of Japanese-American men showed that increase milk consumption was associated with a reduced risk of stroke(8). Building on these findings, over 41,000 Japanese men and women age 40 to 59 years participating in the Japanese Public Health Center study(9) and without a history of CVD or cancer completed a food frequency questionnaire concerning 147 foods. The researchers followed the participants from 1990 to 2003, looking at the incidence of stroke and coronary heart disease in relation to calcium intake. The researchers that, compared to those with the lowest intake of calcium per day (233 mg per day), those with the highest intake of calcium per day (753 mg per day) had a 29% reduced risk of all forms of stroke (ischemic stroke, intraparenchymal hemorrhage, subarachnoid hemorrhage) and a 27% reduced risk of ischemic stroke. When looking at calcium intake from dairy, those with the highest intakes of calcium from dairy (116 mg per day) had a 30% reduced for all forms of stroke and ischemic stroke compared to those with the lowest dairy calcium intake (0 mg per day). No benefits were seen with calcium intake and heart disease. For the researchers, “Dietary calcium intake, especially calcium from dairy products, was found to be associated with a reduced incidence of stroke among middle-aged Japanese.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com Reference: 1 “Impact of Stroke” posted on the American Stroke Association Website www.strokeassociation.org/presenter.jhtml?identifier=1033 2 Poole KE. Reduced vitamin D in acute stroke. Stroke. 2006 Jan;37(1):243-5 3 Spence JD. Vitamin Intervention For Stroke Prevention trial: an efficacy analysis. Stroke. 2005 Nov; 36(11):2404-9. Epub 2005 Oct 20 4 Larsson SC. Folate, Vitamin B6, Vitamin B12, and Methionine Intakes and Risk of Stroke Subtypes in Male Smokers. American Journal of Epidemiology Advance Access published on February 12, 2008. doi:10.1093/aje/kwm395 5 Umesawa M. Dietary Calcium Intake and Risks of Stroke, Its Subtypes, and Coronary Heart Disease in Japanese. The JPHC Study Cohort I. Stroke. 2008 Jul 17. [Epub ahead of print] 6 Hu FB. Vitamin D and Calcium Intake in Relation to Type 2 Diabetes in Women. Diabetes Care 29: 650-656 7 Park SY. Calcium and Vitamin D Intake and Risk of Colorectal Cancer: The Multiethnic Cohort Study. American Journal of Epidemiology Advance Access published on January 10, 2007. Am. J. Epidemiol. 2007 165: 784-793 8 Abbott RD. Effect of dietary calcium and milk consumption on risk of thromboembolic stroke in older middle-aged men: the Honolulu Heart Program. Stroke. 1996;27:813– 818 9 Tsugane S, Sobue T. Baseline survey of JPHC study– design and participation rate: Japan Public Health Center-Based Prospective Study on Cancer and Cardiovascular Diseases. J Epidemiol. 2001;11(suppl): S24–S29 Do you have a question for us? If so please send in your questions to newsletter@herbalremedies.com We will answer all email ASAP!

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For assistance or to purchase products by phone call toll free in the USA 1-866-467- 6444 or World Wide 1-307-577-6444 or e-mail your questions to newsletter@herbalremedies.com. We will answer e-mails in the newsletter as space allows. Our Sponsors HerbalRemedies.com Get the finest all natural health products, get the best service, and low cost worldwide delivery. Enter coupon code "NL102908" when checking out to obtain discounts on your next purchase from www.HerbalRemedies.com How would you like to save $10.49 or more off your next order? You CAN by using your 5% off coupon in conjunction with our $5.49 automatic shipping discount for orders over $95. The more you order the more you save!!! Only one coupon per order!